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FLORFENICOL

FLORFENICOL structure

CAS No:
76639-94-6
Formula:
C12H14Cl2FNO4S
Chemical Name:
FLORFENICOL
Synonyms:
AQUAFEN;NUFLOR;[R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE;SCH-25298;Florfenicol98%Min;FLORFENICAL;FLEROXACINLACTATE;2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]ethanamide
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Appearance: White or off-white crystalline powder Content: (dry product calculation) ≥98% Moisture: ≤0.5% Residue: ≤0.1% Heavy metals: ≤20ppm Acidity: 4.5-6.5 Chloride: ≤0.02% Fluorine: ≥4.8% Relevant substances: Total impurity spots ≤2

ChEBI: Florfenicol is a carboxamide that is the N-dichloroacetyl derivative of (1R,2S)-2-amino-3-fluoro-1-[4-(methanesulfonyl)phenyl]propan-1-ol. A synthetic veterinary antibiotic that is used for treatment of bovine respiratory disease and foot rot; also used in aquaculture. It has a role as an antimicrobial agent. It is a sulfone, a secondary alcohol, an organofluorine compound, an organochlorine compound and a secondary carboxamide. It is functionally related to a dichloroacetic acid.

FLORFENICOL Basic Attributes

Molecular Weight：

358.21

Exact Mass：

358.21

EC Number：

620-107-1

HScode：

29419090

Characteristics

PSA：

91.8

XLogP3：

-0.12

Appearance：

solid

Density：

1.5±0.1 g/cm3

Melting Point：

153°C

Boiling Point：

617.5±55.0 °C at 760 mmHg

Flash Point：

327.3±31.5 °C

Refractive Index：

1.548

Safety Information

wgk germany：

safety instructions：

24/25

Precautionary statement(s)：

P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P501

Hazard Statements：

H302

FLORFENICOL Use and Manufacturing

anticholinergic, antiparkinsonian

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