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Suloctidil

Suloctidil structure

CAS No:
54767-75-8
Formula:
C20H35NOS
Chemical Name:
Suloctidil
Synonyms:
Benzenemethanol,4-[(1-methylethyl)thio]-α-[(1R)-1-(octylamino)ethyl]-,(αS)-;Benzenemethanol,4-[(1-methylethyl)thio]-α-[1-(octylamino)ethyl]-,(R*,S*)-;(αS)-4-[(1-Methylethyl)thio]-α-[(1R)-1-(octylamino)ethyl]benzenemethanol;Suloctidil;Sulocton;CP 556S;Suloctidyl;(±)-Suloctidil;Dulasi;Sudil;Sulodene;Iangene;Bemperil;Cerebro;Fluvisco;Fluversin;Loctidon;Dulcotil;MJF 12637;Euvasal;Circleton;Locton;Hemoantin;Octamet;Polivasal;113409-25-9
Categories:
Analytical Chemistry > Standard

Description

(1S,2R)-2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol is an alkylbenzene.|A peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders. It is hepatotoxic and fatalities have occurred. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1312)

Suloctidil Basic Attributes

Molecular Weight：

337.56

Exact Mass：

337.56

EC Number：

259-332-1

DSSTox ID：

DTXSID4045638

ATC Code：

C - Cardiovascular system

Characteristics

PSA：

57.6

XLogP3：

5.95000

Density：

0.99g/cm3

Melting Point：

62-63 °C

Boiling Point：

467.3ºC at 760 mmHg

Flash Point：

236.4ºC

Refractive Index：

1.528

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

RTECS Number：

DO8910000

Marks：

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

MeSH：

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

MeSH Entry Terms：

CP-556S

Suloctidil Use and Manufacturing

Vasodilator (peripheral).

Computed Properties

Molecular Weight:337.6
XLogP3:5.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:12
Exact Mass:337.24393591
Monoisotopic Mass:337.24393591
Topological Polar Surface Area:57.6
Heavy Atom Count:23
Complexity:277
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes