Novaluron

492.7

492.70

601-443-8

DTXSID5034773

76.7

5.27

white

1.66 g/cm³

176-179 °C

202℃

1.513

In water, 0.9531 mg/l @ 25 deg C

0-6°C

3.75X10-6 mm Hg @ 40 deg C

196.35 Ų [M+H]+ [CCS Type: TW]

UN 3077 9 / PGIII

2

50/53

60-61

N

P273-P501

H410

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

California Environmental Protection Agency/Department of Pesticide Regulation; Toxicology Data Review Summaries. Available from: http://www.cdpr.ca.gov/docs/toxsums/toxsumlist.htm on Novaluron as of April 22, 2003.|US EPA; Pesticide Fact Sheet. Novaluron. Conditional Registration. September 24, 2001. Washington, DC: USEPA, Off Prev Pest Tox Sub (7501C). Available at http://www.epa.gov/opprd001/factsheets/novaluron.pdf as of April 15, 2002.

|Warning|H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]|P273, P391, and P501|Aggregated GHS information provided by 91 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Danger|H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]|P260, P264, P270, P273, P314, P391, and P501

Applicators and other handlers must wear: Long-sleeved shirt and long pants. Chemical resistant gloves such as barrier laminate, butyl rubber, nitrile rubber, neoprene rubber, or Viton. Shoes puls socks. Protective eyewear. Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this product's concentrate. Do not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and hot water. Keep and wash PPE separately form other laundry.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|Users should: Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. Remove clothing immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing.

Causes substantial but temporary eye injury. Do not get in eyes or on clothing. Harmful if absorbed through skin. Avoid contact with skin, eyes, or clothing. ...Prolonged or frequently repeated skin contact may cause allergic reactions in some individuals.

Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics. (See all compounds classified as Insecticides.)

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/|If in eyes: Hold eye open and rinse slowly and gently with water for 15-20 min. Remove contact lenses, if present, after the first 5 min, then continue rinsing eye. Call a poison control center or doctor for treatment advice.|If on skin or clothing: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15-20 min. Call a poison control center or doctor for treatment advice.|For more Antidote and Emergency Treatment (Complete) data for NOVALURON (6 total), please visit the HSDB record page.

/HUMAN EXPOSURE STUDIES/ Causes substantial but temporary eye injury. Do not get in eyes or on clothing. Harmful if absorbed through skin. Avoid contact with skin, eyes, or clothing. ...Prolonged or frequently repeated skin contact may cause allergic reactions in some individuals.|/SPECIAL STUDIES/ Human lymphocytes in whole blood from a healthy male were exposed to concns of GR 572 (Novaluron Technical) (batch no. FCF/T/81-89, purity: 97.5%) ranging from 40-1,000 mg/ml for 24 hrs (non-activation) or 3 hrs (activation), followed by an addnl 21 hrs of incubation in the absence of the test material. The cells were cultured in the presence of colcemid (0.4 mg/ml, final concn) for the final 3 hrs of the incubation. A single trial was performed with triplicate plates for each treatment level. An S9 fraction derived from the liver of rats pretreated with Aroclor 1254 was used to metabolize the test material. There was no treatment-related incr in the incidence of chromosomal aberrations either under conditions of non-activation or activation.

1-(3-chloro-4-(1,1,2-trifluoro-2-trifluoromethoxyethoxy)phenyl)-3-(2,6-difluorobenzoyl)urea

RimOn; 10% emulsifiable concentrate

Agrochemicals -> Insecticides|Insecticides|Environmental transformation -> Pesticides (parent, predecessor)

Novaluron has known environmental transformation products that include 275-309-I, 275-352-I, CGA 149772, and CGA 149776.