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Olpadronic acid

Olpadronic acid structure

Olpadronic acid 

structure
  • CAS No:

    63132-39-8

  • Formula:

    C5H15NO7P2

  • Chemical Name:

    Olpadronic acid

  • Synonyms:

    Phosphonic acid,P,P′-[3-(dimethylamino)-1-hydroxypropylidene]bis-;Phosphonic acid,[3-(dimethylamino)-1-hydroxypropylidene]bis-;P,P′-[3-(Dimethylamino)-1-hydroxypropylidene]bis[phosphonic acid];3-Dimethylamino-1-hydroxypropylidenebiphosphonic acid;Olpadronic acid;3-(Dimethylamino)-1-hydroxypropylidene-1,1-bisphosphonic acid;[3-(Dimethylamino)-1-hydroxy-1-phosphonopropyl]phosphonic acid;3-Dimethylamino-1-hydroxypropane-1,1-diphosphonic acid

  • Categories:

    Organic Chemistry  >  Phosphines

Olpadronic acid Basic Attributes

263.121

263.12

874HHB2V3S

DTXSID50212479

2931900090

Characteristics

139

-5.9

1.706g/cm3

590.1ºC at 760 mmHg

310.7ºC

1.566

Safety Information

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES such as OSTEOPOROSIS. (See all compounds classified as Bone Density Conservation Agents.)

(3-dimethylamino-1-hydroxypropylidene)-1,1-biphosphonate

Olpadronic acid Use and Manufacturing

Used for the preparation of bisphosphonic acid derivatives as anti-osteoporosis

Computed Properties

Molecular Weight:263.12
XLogP3:-5.9
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:263.03237581
Monoisotopic Mass:263.03237581
Topological Polar Surface Area:139
Heavy Atom Count:15
Complexity:283
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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