Ammonium hexafluorosilicate

178.15

178.03600

240-968-3

1X545W620G

2854

DTXSID6047076

CRYSTALLINE POWDER|White cubic or trigonal crystals.

2

2.89280

White Crystalline Powder and Chunks

2.011 g/cm³

°Cd ec.)

Slightly soluble in water. Insoluble in alcohol and acetone.

Store in a tightly closed container. Do not store in glass. Store in a cool, dry area away from incompatible substances.

ODORLESS

MP: DECOMP; INDEX OF REFRACTION: 1.3696 (ALPHA); DENSITY: 2.011 (ALPHA), 2.152 (BETA); (ALPHA) OCTAGONAL CRYSTALS, (BETA) HEXAGONAL CRYSTALS, COLORLESS|Heat of soln: 85 BTU/lb= 47 cal/g= 2.0X10+5 J/kg|Hydrolyzed to fluoride ion, esp in alkaline water /Fluosilicate salts/|Solutions of fluosilicates are sensitive to hydrolysis in alkaline medium. In the presence of acid, fluosilicate solutions release silicon tetrafluoride. The thermal decomposition of fluosilicates takes place with release of gaseous silicon tetrfluoride and formation of the solid fluoride. /Fluosilicates/

Water soluble.

Salts, Basic

Water-Reactive

Salts, basic, such as AMMONIUM FLUOROSILICATE, are generally soluble in water. The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids. These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Ammonium fluorosilicate reacts with water to form hydrofluoric acid, a source of fluoride ions. Unlike other halide ions, the fluoride ion is quite reactive, acting as a weak base and participating in some unique reactions. In particular, fluorides react strongly with compounds containing calcium, magnesium, or silicon ions, which means that solutions containing soluble fluorides are corrosive to both living tissue and glass. Hydrofluoric acid can cause severe chemical burns and is one of the few materials that can etch glass. It is also a toxic gas in its anhydrous form.

Corrosive to aluminum

III

6.1

UN 2854 6.1/PG 3

2

23/24/25

26-45

VV7800000

T

Toxic

Stable under normal temperatures and pressures.

P261-P280-P301 + P310-P311

H301-H311-H331

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Ammonium silicofluoride is an indirect food additive for use only as a component of adhesives. For use only as a bonding agent for aluminum foil, stabilizer, or preservative. Total fluoride from all sources not to exceed one percent by weight of the finished adhesive.

WHO; Environ Health Criteria: Fluorine and Fluorides p.49 (1984).|USEPA, Office of Drinking Water; Criteria Document (Draft): Fluoride (1985).

Special Hazards of Combustion Products: Toxic and irritating hydrogen fluoride, silicon tetrafluoride, and oxides of nitrogen may form in fires. (USCG, 1999)

|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P311, P312, P321, P322, P330, P361, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 218 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H301: Toxic if swallowed [Danger Acute toxicity, oral]|P260, P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P311, P312, P314, P321, P322, P330, P337+P313, P361, P363, P403+P233, P405, and P501|P260, P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P314, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501

Excerpt from ERG Guide 151 [Substances - Toxic (Non-combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 151 [Substances - Toxic (Non-combustible)]: Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2016)

Dust respirator; acid-resistant clothing and hat; rubber gloves; goggles and safety shoes (USCG, 1999)|/Wear/ dust respirator, acid-resistant clothing and hat; rubber gloves; goggles and safety shoes.

Not flammable

Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.)

Environmental considerations- land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.|Environmental considerations- water spill: Use natural deep water pockets, excavated lagoons, or sand bag barriers to trap material at bottom. Remove trapped material with suction hoses.|Environmental considerations- air spill: Vapor knockdown water is corrosive or toxic and should be diked for containment.

If material not involved in fire: Keep material out of water sources and sewers. Build dikes to contain flow as necessary.|Keep upwind. Avoid breathing vapors or dusts. Wash away any material which may have contacted the body with copious amt of water or soap and water.|SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers.|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

/GUIDE 151: SUBSTANCES - TOXIC (Non-combustible)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.|/GUIDE 151: SUBSTANCES - TOXIC (Non-combustible)/ Health: Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.|/GUIDE 151: SUBSTANCES - TOXIC (Non-combustible)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas.|/GUIDE 151: SUBSTANCES - TOXIC (Non-combustible)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.|For more DOT Emergency Guidelines (Complete) data for AMMONIUM SILICOFLUORIDE (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

STRONG IRRITANT TO EYES & SKIN.

Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 2.5 mg/cu m. /Fluorides as F/|Permissible Exposure Limit: Table Z-2 8-hr Time Weighted Avg: 2.5 mg/cu m. /Fluoride as dust/

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

Populations that appear to be at increased risk form the effects of fluoride are individuals that suffer for diabetes insipidus or some forms of renal impairment. /Fluoride/

OCCURS IN NATURE AS MINERAL CRYPTOHALITE.

Food and Environmental Agents: Effect on Breast-Feeding: Reported Sign or Symptom in Infant or Effect on Lactation: Fluorides: None. /from Table 7/

FLUORIDES ARE ABSORBED FROM GI TRACT, LUNG, & SKIN. GI TRACT IS MAJOR SITE OF ABSORPTION. THE RELATIVELY SOL CMPD, SUCH AS SODIUM FLUORIDE, ARE ALMOST COMPLETELY ABSORBED ... FLUORIDE HAS BEEN DETECTED IN ALL ORGANS & TISSUES EXAMINED. ... THERE IS NO EVIDENCE THAT IT IS CONCENTRATED IN ANY TISSUES EXCEPT BONE, THYROID, AORTA, & PERHAPS KIDNEY. FLUORIDE IS PREPONDERANTLY DEPOSITED IN THE SKELETON & TEETH, & THE DEGREE OF SKELETAL STORAGE IS RELATED TO INTAKE AND AGE. ... A FUNCTION OF THE TURNOVER RATE OF SKELETAL COMPONENTS, WITH GROWING BONE SHOWING GREATER FLUORIDE DEPOSITION THAN BONE IN MATURE ANIMALS. ... MAJOR ROUTE OF ... EXCRETION IS BY WAY OF KIDNEYS ... ALSO EXCRETED IN SMALL AMT BY SWEAT GLANDS, LACTATING BREAST, & GI TRACT. ... ABOUT 90% OF FLUORIDE ION FILTERED BY GLOMERULUS IS REABSORBED BY RENAL TUBULES. /FLUORIDE/|/RENAL CLEARANCE/ 1. VIRTUALLY ALL FLUORIDE IN PLASMA ... IS ULTRAFILTERABLE. 2. RENAL EXCRETION OF RADIOFLUORIDE DEPENDS ON GLOMERULAR FILTRATION & VARIABLE TUBULAR REABSORPTION. 3. PROBABLY, REABSORPTION IS LARGELY PASSIVE ... 4. FLUORIDE EXCRETION INCR WHEN PLASMA CONCN IS INCREASED. 5. PROCEDURES THAT INCREASE URINARY FLOW RATE (EG, ADMIN OF OSMOTIC DIURETICS, HYPERTONIC SALINE, OR DIURETIC DRUGS) INCREASE THE CLEARANCE OF FLUORIDE. /FLUORIDE/|IN FEMALE RATS, THE SKELETONS OF YOUNGER RATS APPARENTLY ARE MORE EFFICIENT AT REMOVING FLUORIDE FROM CIRCULATION THAN ARE THOSE OF OLDER RATS. /SODIUM FLUORIDE/|Following ingestion, soluble fluorides are rapidly absorbed from the gastrointestinal tract at least to the extent of 97%. Absorbed fluoride is distributed throughout the tissues of the body by the blood. Fluoride concn in soft tissues fall to exposure levels within a few hours of exposure. Fluoride exchanges with hydroxyl radicals of hydroxyapatite (the inorganic constituent of bone) to form fluorohydroxyapatite. Fluoride that is not retained is excreted rapidly in urine. In adults under steady state intake conditions, the urinary concn of fluoride tends to approximate the concn of fluoride in the drinking water. This reflects the decreasing retention of fluoride (primarily in bone) with increasing age. Under certain conditions perspiration may be an important route of fluoride excretion. The concn of fluoride retained in bones and teeth is a function of both the concn of fluoride intake and the duration of exposure. Periods of excessive fluoride exposure will result in increased retention in the bone. However, when the excessive exposure is eliminated, the bone fluoride concn will decrease to a concn that is again reflective of intake. /Fluoride/

INHIBITION OF ONE OR MORE ENZYMES CONTROLLING CELLULAR GLYCOLYSIS (& PERHAPS RESP) MAY RESULT IN A CRITICAL LESION. ... BINDING OR PRECIPITATION OF CALCIUM AS CALCIUM FLUORIDE ... SUGGESTED AS MECHANISM UNDERLYING MANY DIVERSE SIGNS & SYMPTOMS IN FLUORIDE POISONING, PARTICULARLY IF DEATH IS DELAYED. ... AT LEAST IN SOME SPECIES FLUORIDE INTERFERES WITH BOTH CONTRACTILE POWER OF HEART AND THE MECHANISM OF BEAT IN A WAY THAT CANNOT BE ASCRIBED TO HYPOCALCEMIA. /FLUORIDE/

Inhalation of dust can cause pulmonary irritation and can be fatal in some cases. Ingestion may be fatal. Contact with dust causes irritation of eyes and irritation or ulceration of skin. (USCG, 1999)

INHALATION: remove patient to fresh air. INGESTION: cause vomiting by giving soapy water or mustard water; have patient drink large quantities of lime water; if necessary, give stimulant such as strong coffee; keep patient warm. EYES: flush with water for 20 min., holding eyelids open. SKIN: wash with soap and water. (USCG, 1999)

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 m1 of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Fluorine and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who Is unconscious or in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W TKO /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's to support vital signs if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Fluorine and related compounds/

SYMPTOMATOLOGY: A. Ingestion of soluble fluoride salts. 1. Salty or soapy taste, salivation, nausea. Repeated small doses (as in drinking water) may produce no other symptoms, but polyuria and polydipsia have also been reported. 2. Large doses lead promptly to burning or crampy abdominal pain, intense vomiting and diarrhea, often with hematemesis and melena. Dehydration and thirst. 3. Muscle weakness, tremors, and rarely transient epileptiform convulsions, preceded or followed by progressive central nervous depression (lethargy, coma and respiratory arrest, even in the absence of circulatory failure). 4. Shock characterized by pallor, weak and thready pulse (sometimes irregular), shallow unlabored respiration, weak heart sounds, wet cold skin, cyanosis, anuria, dilated pupils, followed almost invariably by death in 2 to 4 hours. 5. Even in the absence of shock, arrhythmias may occur, especially multiple episodes of ventricular fibrillation leading eventually to cardiac arrest. 6. If the victim survives a few hours, paralysis of the muscles of deglutition, carpopedal spasm, and painful spasms of the extremities. 7. Occasionally localized or generalized urticaria. 8. The above signs and symptoms are related to a variety of metabolic disorders that may occur in acute fluoride poisoning, including hypocalcemia, hypomagnesemia, metabolic and/or respiratory acidosis and sometimes hyperkalemia. /Fluoride/|INITIAL SYMPTOMS FROM INGESTION INCLUDE ... SALIVATION, NAUSEA, ABDOMINAL PAIN, VOMITING, AND DIARRHEA ARE FREQUENT. ... THE PATIENT SHOWS SIGNS OF INCR IRRITABILITY OF THE NERVOUS SYSTEM ... HYPOCALCEMIA & HYPOGLYCEMIA ARE FREQUENT LAB FINDINGS. ... BLOOD PRESSURE FALLS ... DUE TO CENTRAL VASOMOTOR DEPRESSION AS WELL AS DIRECT TOXIC ACTION ON CARDIAC MUSCLE. THE RESPIRATORY CENTER IS FIRST STIMULATED & LATER DEPRESSED. DEATH ... FROM EITHER RESPIRATORY PARALYSIS OR CARDIAC FAILURE. /FLUORIDE SALTS/|... THE MAJOR MANIFESTATIONS OF CHRONIC INGESTION OF EXCESSIVE AMT OF FLUORIDE ARE OSTEOSCLEROSIS & MOTTLED ENAMEL. ... DENSITY AND CALCIFICATION OF BONE ARE INCREASED ... THOUGHT TO REPRESENT THE REPLACEMENT OF HYDROXYAPATITE BY THE DENSER FLUOROAPATITE. /FLUORIDE SALTS/|CHRONIC POISONING: INTAKE OF MORE THAN 6 MG ... /A/ DAY RESULTS IN FLUOROSIS. SYMPTOMS ARE WT LOSS ... ANEMIA, WEAKNESS, GENERAL ILL HEALTH, STIFFNESS OF JOINTS ... ./FLUORIDE/|TOXIC BY INHALATION.

ammonium hexafluorosilicate

CHEMICAL COMPOSITION /OF DRI-DIE IS/ SILICA AEROGEL WITH AMMONIUM FLUOSILICATE TO 3% FLUORINE CONTENT.|/DRIANONE IS A/ FORMULATION OF AMMONIUM FLUOSILICATE, PYRETHRINS, PIPERONYL BUTOXIDE WITH SILICA GEL AND OIL|Grades or purity: Pure, 99+%; commercial, 98+%|Laidlaw U-San-O Moth proofing spray: Soluble concentrate, 13.5% ammonium fluosilicate as active ingredient.|For more Formulations/Preparations (Complete) data for AMMONIUM SILICOFLUORIDE (6 total), please visit the HSDB record page.

Wholesale and retail trade|Silicate(2-), hexafluoro-, ammonium (1:2): ACTIVE|Ammonium bifluoride solubilizes silica and silicates by forming ammonium fluorosilicate ... .|Vacuum crystallization is necessary to increase the yield, or crystallization must be carried out at low temperature. The precipitates are washed and dried.

AOAC Method 945.05. Fluorine Present as Sodium Fluosilicate in Pesticide Formulations. /Sodium silicofluoride/

MATRIX: URINE: PROCEDURE: ION SPECIFIC ELECTRODE; RANGE: LOWER LIMIT URINE 0.19 MG/L. /TOTAL FLUORIDE/|CHARGED PARTICLE ACTIVATION TECHNIQUE IS USEFUL IN NONDESTRUCTIVELY DETERMINING CONCN PROFILES OF F- IN EXTRACTED TEETH. /FLUORIDE/|NIOSH 8308: Analyte: fluoride ion (F-); Specimen: urine, pre- and post-shift; Vol: 50 ml in chemically clean polyethylene bottles; Preservative: 0.2 g EDTA added to bottles before collection; Stability: 2 wk @ 4 °C, longer if frozen; Technique: ion selective electrode; Quality control: spike urine pools, correct for creatinine content; Range: 1-100 mg/l urine; Est LOD: 0.1 mg/l urine; Precision(Sr): 0.04; Interferences: Hydroxide, the only positive interference, is eliminated by use of the buffer /Fluoride in urine/

Cosmetics -> Antiplaque; Oral care