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5-Amino-2-methylbenzenesulfonamide

5-Amino-2-methylbenzenesulfonamide structure

5-Amino-2-methylbenzenesulfonamide 

structure
  • CAS No:

    6973-09-7

  • Formula:

    C7H10N2O2S

  • Chemical Name:

    5-Amino-2-methylbenzenesulfonamide

  • Synonyms:

    Benzenesulfonamide,5-amino-2-methyl-;5-Amino-2-methylbenzenesulfonamide;3-Amino-6-methylbenzenesulfonamide;NSC 36969;3-Aminosulfonyl-4-methylaniline;2-Methyl-5-amino-benzenesulfonamide

  • Categories:

    Specialty Chemicals

5-Amino-2-methylbenzenesulfonamide Basic Attributes

186.23

186.23

1592732-453-0

36969

DTXSID40284367

2935009090

Characteristics

94.6

0.2

1.4±0.1 g/cm3

163-164℃

421.5±55.0 °C at 760 mmHg

208.7±31.5 °C

1.609

Safety Information

NONH for all modes of transport

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

H315

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 9 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

5-Amino-2-methylbenzenesulfonamide Use and Manufacturing

5-Amino-2-methylbenzenesulfonamide is an intermediate for the synthesis of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

Computed Properties

Molecular Weight:186.23
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:186.04629874
Monoisotopic Mass:186.04629874
Topological Polar Surface Area:94.6
Heavy Atom Count:12
Complexity:245
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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