Hydrazine, (3,4-dichlorophenyl)-, hydrochloride (1:1)

white to light yellow crystal powde

(A) In a 1000 ml three-necked flask, add 3, 4-dichloroaniline (1) (64.8 g), 200 ml of concentrated hydrochloric acid and 100 ml of water, heat to 80°C, and mechanically stir at high speed for 40 minutes until the material forms a slurry. Transfer it to a 1000ml beaker and cool in an ice bath until the temperature is lower than 5°C; take a 100ml beaker, add sodium nitrite (31.2g) and 50ml of water, stir to dissolve the ice bath and cool to a temperature lower than 5°C; The sodium nitrite solution was slowly added to the slurry liquid, kept at a temperature of 5°C for 1 hour, filtered to give a diazo solution and transferred to a 2000 ml beaker; a 250 ml beaker was added and 200 ml concentrated. Hydrochloric acid and stannous chloride dihydrate (188g), taking a constant temperature funnel 250ml, placed in a large beaker 2000ml, the mixed solution of stannous chloride dihydrate and concentrated hydrochloric acid was slowly added to the slurry through a constant temperature funnel; Adjust the temperature to 25°C, stir with a mechanical stirrer for 1 hour, and filter to obtain a yellowish-yellow powder. Add the powder to 80°C water, stir and dissolve, filter, cool and crystallize, and filter.White needle crystals; the remaining filtrate temperature was adjusted to 50 °C, rotary evaporation, cooling to give a white powder; white needle crystals and white powder were combined, washed with dilute hydrochloric acid, filtered, and dried to give a white solid powder 3, 4- Dichlorophenylhydrazine hydrochloride (2) (72.6 g);

Molecular Weight:213.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:211.967481
Monoisotopic Mass:211.967481
Topological Polar Surface Area:38
Heavy Atom Count:11
Complexity:110
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes