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Spinosin

Spinosin structure

Spinosin 

structure
  • CAS No:

    72063-39-9

  • Formula:

    C28H32O15

  • Chemical Name:

    Spinosin

  • Synonyms:

    4H-1-Benzopyran-4-one,6-(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-;6-(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one;Spinosin;Flavoayamenin;Swertisin 2′′-O-glucoside

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

Spinosyn a C-glycoside flavonoid isolated from the seeds of Zizyphus jujube, with neuroprotective effects. Spinosin inhibits Aβ1-42 production and aggregation via activating Nrf2/HO-1 pathway[1][2][3].


Spinosin is a flavone C-glycoside that is flavone substituted by hydroxy groups at positions 5 and 4', a methoxy group at position 7 and a 2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl residue at position 6 via a C-glycosidic linkage. It has a role as a plant metabolite and an anxiolytic drug. It is a flavone C-glycoside, a dihydroxyflavone and a monomethoxyflavone. It derives from a flavone.

Spinosin Basic Attributes

608.546

608.54

DTXSID50222396

29329990

Characteristics

245

-1.1

1.7±0.1 g/cm3

149 °C

901.4°C at 760 mmHg

296.7±27.8 °C

1.734

Safety Information

24/25

Drug Information

spinosin

Computed Properties

Molecular Weight:608.5
XLogP3:-1.1
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:7
Exact Mass:608.17412031
Monoisotopic Mass:608.17412031
Topological Polar Surface Area:245
Heavy Atom Count:43
Complexity:987
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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