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Home > Encyclopedia > Z-3-CYCLOHEXYL-L-ALANINE

Z-3-CYCLOHEXYL-L-ALANINE

Z-3-CYCLOHEXYL-L-ALANINE structure

Z-3-CYCLOHEXYL-L-ALANINE 

structure
  • CAS No:

    25341-42-8

  • Formula:

    C17H23NO4

  • Chemical Name:

    Z-3-CYCLOHEXYL-L-ALANINE

  • Synonyms:

    Z-BETA-CYCLOHEXYLALANINE;Z-CHA-OH;Z-3-CYCLOHEXYL-L-ALANINE;Z-L-CYCLOHEXYLALANINE;CBZ-L-CYCLOHEXYLALANINE;(S)-2-(benzyloxycarbonylamino)-3-cyclohexylpropanoic acid;(2S)-[(Benzyloxycarbonyl)amino]-3-cyclohexylpropionic acid;(S)-N-(Benzyloxycarbonyl)cyclohexylalanine

  • Categories:

    Biochemical Engineering  >  Amino Acids and Derivatives

Description

Transparent, yellow oil

Z-3-CYCLOHEXYL-L-ALANINE Basic Attributes

305.37

305.162720

DTXSID50556769

2924299090

Characteristics

75.6

4.2

1.2±0.1 g/cm3

257.1±28.2 °C

1.542

Safety Information

3

Z-3-CYCLOHEXYL-L-ALANINE Use and Manufacturing

To a O9C solution of 3-cyclohexyl-L-alanine (10g, 58.4mmol) in THF/ H2O ( 1/1 , 292ml) was added benzyl chloroformate (9.93 g, 58.4 mmol) and K2CO3 (9.67g, 70.09 mmol). The mixture was stirred at 0s C for 0.5 hour, and then stirred overnight at RT. The reaction mixture was diluted with EtOAc (200ml) and adjusted the pH to about 2 with 6 N HCI. The organic layer was washed with brine, dried (MgSO4), filtered and concentrated to a solid as product in 95percent yield (17g): MS (m/z): 306(M+H).

Computed Properties

Molecular Weight:305.4
XLogP3:4.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:305.16270821
Monoisotopic Mass:305.16270821
Topological Polar Surface Area:75.6
Heavy Atom Count:22
Complexity:360
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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