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Home > Encyclopedia > TYRPHOSTIN AG 126

TYRPHOSTIN AG 126

TYRPHOSTIN AG 126 structure

TYRPHOSTIN AG 126 

structure
  • CAS No:

    118409-62-4

  • Formula:

    C10H5N3O3

  • Chemical Name:

    TYRPHOSTIN AG 126

  • Synonyms:

    RARECHEM AL BX 0673;TYRPHOSTIN A10;TYRPHOSTIN AG 126;ag127;AG 126;ALPHA-CYANO-(3-HYDROXY-4-NITRO)CINNAMONITRILE;[3-HYDROXY-4-NITROBENZYLIDENE]MALONONITRILE;Tyrphostin126

  • Categories:

    Biochemical Engineering  >  Amino Acids and Derivatives

Description

AG126 is a tyrosine kinase inhibitor which can prevent the activation of mitogen-activated protein kinase p42MAPK (ERK2).


2-[(3-hydroxy-4-nitrophenyl)methylidene]propanedinitrile is a nitrophenol.

TYRPHOSTIN AG 126 Basic Attributes

215.16

215.033096

7YA4AMD1JC

DTXSID80152117

Characteristics

114

2

1.5±0.1 g/cm3

184.8±27.9 °C

1.689

−20°C

Safety Information

6.1

2811

3

23/24/25

26-36-45

T

P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P311, P312, P321, P322, P330, P361, P363, P403+P233, P405, P501

H301

|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P311, P312, P321, P322, P330, P361, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)

AG 126

Computed Properties

Molecular Weight:215.16
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:215.03309103
Monoisotopic Mass:215.03309103
Topological Polar Surface Area:114
Heavy Atom Count:16
Complexity:388
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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