N-tert-Butoxycarbonyl-O-benzylthreonine
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N-tert-Butoxycarbonyl-O-benzylthreonine
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CAS No:
15260-10-3
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Formula:
C16H23NO5
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Chemical Name:
N-tert-Butoxycarbonyl-O-benzylthreonine
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Synonyms:
L-Threonine,N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-;Butyric acid,3-(benzyloxy)-2-(carboxyamino)-,N-tert-butyl ester,Ls-threo-;N-[(1,1-Dimethylethoxy)carbonyl]-O-(phenylmethyl)-L-threonine;N-tert-Butoxycarbonyl-O-benzyl-L-threonine;N-(tert-Butyloxycarbonyl)-O-benzyl-L-threonine;tert-Butoxycarbonyl-O-benzylthreonine;N-tert-Butoxycarbonyl-O-benzylthreonine;N-(tert-Butoxycarbonyl)threonine benzyl ether;(2S,3R)-2-(tert-Butoxycarbonylamino)-3-benzyloxybutanoic acid;NSC 334365;(2S,3R)-3-Benzyloxy-2-(tert-butoxycarbonylamino)butanoic acid;N-Boc-O-benzyl-L-threonine;Boc-L-Thr(OBn)-OH;54784-63-3;111516-03-1;172846-16-1;1416064-93-1;1422430-41-8;1453873-39-6
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CAS No:
Characteristics
84.9
2.3
White to off-white crystalline powder
1.152±0.06 g/cm3(Predicted)
80-82 °C(lit.)
461.5±45.0 °C(Predicted)
232.9±28.7 °C
16.5 ° (C=1, MeOH)
2-8°C
1.36E-07mmHg at 25°C
22 º (c=2 in 95% ethanol)
Safety Information
NONH for all modes of transport
3
22-24/25
Stable under normal temperatures and pressures.
N-tert-Butoxycarbonyl-O-benzylthreonine Use and Manufacturing
Suspend O-benzyl-L-threonine in a dioxane solution, acylate with tert-butoxycarbonyl azide to obtain a crude product, and extract it with ethyl acetate at a pH of 9-10 , And then refined by recrystallization.
Used for peptide synthesis and as amino acid protection monomer.
L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-: INACTIVE
Computed Properties
Molecular Weight:309.36
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:309.15762283
Monoisotopic Mass:309.15762283
Topological Polar Surface Area:84.9
Heavy Atom Count:22
Complexity:371
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of N-tert-Butoxycarbonyl-O-benzylthreonine
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Business licensed Certified factoryManufactory Supplier of Pharmaceutical Peptide,Cosmetic peptide,Custom peptides,API polypeptide,Amino acids and derivativesInquiryCAS No.: 15260-10-3Grade: Research and Industrial GradeContent: 98.00% -
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N-tert-Butoxycarbonyl-O-benzylthreonine
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