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8-Bromo-cAMP

8-Bromo-cAMP structure

CAS No:
23583-48-4
Formula:
C10H11BrN5O6P
Chemical Name:
8-Bromo-cAMP
Synonyms:
Adenosine,8-bromo-,cyclic 3′,5′-(hydrogen phosphate);4H-Furo[3,2-d]-1,3,2-dioxaphosphorin,adenosine deriv.;8-Bromo-cyclic 3′,5′-AMP;8-Bromoadenosine cyclic 3′,5′-phosphate;Cyclic 8-bromoadenosine 3′,5′-monophosphate;8-Bromo-cAMP;8-Bromoadenosine cyclic 3′,5′-monophosphate;NSC 171719;8-Bromoadenosine-cAMP;37050-48-9
Categories:
Biochemical Engineering > Saccharides

Description

White powder

8-Br-cAMP is a 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP bearing an additional bromo substituent at position 8 on the adenine ring. An activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase. It has a role as a protein kinase agonist and an antidepressant. It is a 3',5'-cyclic purine nucleotide, an organobromine compound and an adenyl ribonucleotide. It derives from a 3',5'-cyclic AMP.|A long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase.

8-Bromo-cAMP Basic Attributes

Molecular Weight：

408.1

Exact Mass：

408.10

EC Number：

245-760-6

UNII：

5QO1UW05Q5

DSSTox ID：

DTXSID1040403

HScode：

29349990

Characteristics

PSA：

155

XLogP3：

0.52630

Appearance：

Pale Brown Powder

Density：

2.8 g/cm3

Melting Point：

254 °C (dec.)(lit.)

Boiling Point：

741.9ºC at 760 mmHg

Flash Point：

402.5ºC

Refractive Index：

2.037

Water Solubility：

aqueous base: soluble

Storage Conditions：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

22-24/25

Drug Information

MeSH Entry Terms：

8 Br Cyclic AMP

Computed Properties

Molecular Weight:408.10
XLogP3:-1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:1
Exact Mass:406.96303
Monoisotopic Mass:406.96303
Topological Polar Surface Area:155
Heavy Atom Count:23
Complexity:532
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Guide of 8-Bromo-cAMP

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Computed Properties
Learn More Other Chemicals

8-Bromo-cAMP

SDS

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