LY-2584702 (tosylate salt)
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LY-2584702 (tosylate salt)
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CAS No:
1082949-68-5
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Formula:
C28H27F4N7O3S
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Chemical Name:
LY-2584702 (tosylate salt)
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Synonyms:
4-[4-[4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate (1:1);LY-2584702 (tosylate salt);LY2584702 Tosylate;4-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-1H-pyrazolo[3,4-d]pyrimidine p-toluenesulfonate
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CAS No:
Description
LY-2584702 tosylate salt is a selective ATP competitive inhibitor of p70S6K with an IC50 of 4 nM. In S6K1 enzyme assay, the IC50 of LY-2584702 is 2 nM.
Computed Properties
Molecular Weight:617.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:4
Exact Mass:617.18322157
Monoisotopic Mass:617.18322157
Topological Polar Surface Area:138
Heavy Atom Count:43
Complexity:851
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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