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Loxistatin acid

Loxistatin acid structure

CAS No:
76684-89-4
Formula:
C15H26N2O5
Chemical Name:
Loxistatin acid
Synonyms:
2-Oxiranecarboxylic acid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)-;Oxiranecarboxylic acid,3-[[[3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,[2S-[2α,3β(R*)]]-;Oxiranecarboxylic acid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)-;(2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid;Ep 475;E 64c;Ep 475 (enzyme inhibitor);Loxistatin acid;NSC 694279
Categories:
Biochemical Engineering > Inhibitors

Description

E 64c is a derivative of naturally occurring epoxide inhibitor of cysteine proteases, a Calcium-activated neutral protease (CANP) inhibitor and a very weak irreversible cathepsin C inhibitor.

Loxistatin acid Basic Attributes

Molecular Weight：

314.38

Exact Mass：

314.38

HScode：

29241990

Characteristics

PSA：

108

XLogP3：

1.36

Density：

1.2±0.1 g/cm3

Boiling Point：

596.4±50.0 °C at 760 mmHg

Flash Point：

314.5±30.1 °C

Refractive Index：

1.504

Storage Conditions：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

RTECS Number：

RR0404200

Drug Information

MeSH Entry Terms：

2,3-epoxysuccinyl-L-leucylamido-3-methylbutane

Computed Properties

Molecular Weight:314.38
XLogP3:1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:314.18417193
Monoisotopic Mass:314.18417193
Topological Polar Surface Area:108
Heavy Atom Count:22
Complexity:422
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes