Z-Guggulsterone
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Z-Guggulsterone
structure -
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CAS No:
39025-23-5
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Formula:
C21H28O2
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Chemical Name:
Z-Guggulsterone
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Synonyms:
Pregna-4,17(20)-diene-3,16-dione,(17Z)-;(17Z)-Pregna-4,17(20)-diene-3,16-dione;(17Z)-Guggulsterone;Z-Guggulsterone;4,17(20)-cis-Pregnadiene-3,6-dione;cis-Guggulsterone;137682-26-9
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CAS No:
Description
Z-guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis[1].
Characteristics
34.1
3.65
light yellow powder
1.1±0.1 g/cm3
174-178 °C
463.3±45.0 °C at 760 mmHg
172.3±25.7 °C
1.557
DMSO: 5 mg/mL
2-8°C
D26 -61° (c = 1 in chloroform)
Safety Information
NONH for all modes of transport
3
37-38
36
Xi
P264, P280, P302+P352, P321, P332+P313, P362
H315
Z-Guggulsterone Use and Manufacturing
Z-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.
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