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Home > Encyclopedia > 3′,4′,5,5′,7-Pentamethoxyflavone

3′,4′,5,5′,7-Pentamethoxyflavone

3′,4′,5,5′,7-Pentamethoxyflavone structure

3′,4′,5,5′,7-Pentamethoxyflavone 

structure
  • CAS No:

    53350-26-8

  • Formula:

    C20H20O7

  • Chemical Name:

    3′,4′,5,5′,7-Pentamethoxyflavone

  • Synonyms:

    4H-1-Benzopyran-4-one,5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-;Flavone,3′,4′,5,5′,7-pentamethoxy-;5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one;3′,4′,5,5′,7-Pentamethoxyflavone;Tricetin pentamethyl ether;3′,4′,5′,5,7-Pentamethoxyflavone;5,7,3′,4′,5′-Pentamethoxyflavone

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic drugs by inhibition of Nrf2 pathway[1].

3′,4′,5,5′,7-Pentamethoxyflavone Basic Attributes

372.37

372.37

DTXSID50333239

2914509090

Characteristics

72.4

3.50300

1.244g/cm3

192-193 °C

554.4ºC at 760mmHg

243.5ºC

1.565

Safety Information

S22-S24/25

Drug Information

3',4',5',5,7-pentamethoxyflavone

3′,4′,5,5′,7-Pentamethoxyflavone Use and Manufacturing

Uses

Inhibits ATPase activity and has chemisensitizing effects

Polyketides [PK] -> Flavonoids [PK12] -> Flavones and Flavonols [PK1211]

Computed Properties

Molecular Weight:372.4
XLogP3:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:372.12090297
Monoisotopic Mass:372.12090297
Topological Polar Surface Area:72.4
Heavy Atom Count:27
Complexity:534
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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