Ligustrazine hydrochloride
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Ligustrazine hydrochloride
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CAS No:
76494-51-4
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Formula:
C8H12N2.xClH
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Chemical Name:
Ligustrazine hydrochloride
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Synonyms:
Pyrazine,2,3,5,6-tetramethyl-,hydrochloride (1:?);Pyrazine,tetramethyl-,hydrochloride;Tetramethylpyrazine hydrochloride;Chuanxiongzine hydrochloride;Ligustrazine hydrochloride
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CAS No:
Description
Ligustrazine (hydrochloride) is a natural product.IC50 value:Target:In vitro: Ligustrazine hydrochloride displayed a protection effect on injured ECV304 cells, NOS and NO formation were significantly increased compared with the model group [1].In vivo:
Drug Information
Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)
chuanxiongzine
Ligustrazine hydrochloride Use and Manufacturing
Anti-platelet coagulation, dilation of small arteries, treatment of occlusive cerebrovascular disease.
Computed Properties
Molecular Weight:172.65
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:172.0767261
Monoisotopic Mass:172.0767261
Topological Polar Surface Area:25.8
Heavy Atom Count:11
Complexity:87.8
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
It can dilate the coronary artery, lower blood pressure, improve myocardial hypoxia tolerance, inhibit platelet aggregation, excite the respiratory center, relax bronchial smooth muscle, improve ventilation function, prevent the formation of immune complexes, inhibit the growth of pathogens, promote inflammation absorption, enhance capillary density, reduce blood viscosity, improve microcirculation, increase cerebral blood flow, resist thrombosis and dissolve thrombus
Registered Holders
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Ruisheng Pharmaceutical (Henan) Co., Ltd.
Active
China
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Sichuan Yinodabo Pharmaceutical Technology Co., Ltd.
Active
China
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ZHONGFU Pharmaceutical Co., Ltd.
Active
China
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