[10]-Gingerol
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[10]-Gingerol
structure -
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CAS No:
23513-15-7
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Formula:
C21H34O4
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Chemical Name:
[10]-Gingerol
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Synonyms:
3-Tetradecanone,5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-,(5S)-;3-Tetradecanone,5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-,(S)-;(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone;[10]-Gingerol;(+)-(S)-[10]-Gingerol;(5S)-[10]-Gingerol;(S)-[10]-Gingerol;(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one;39886-87-8
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CAS No:
Description
10-Gingerol is a major pungent constituent in the ginger oleoresin from fresh rhizome, with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM[1][2].
(10)-Gingerol is a beta-hydroxy ketone, a member of phenols and a monomethoxybenzene.
Characteristics
66.8
4.61
Yellow-brown Fine Powder
1.0±0.1 g/cm3
56-58 °C
499.7±35.0 °C at 760 mmHg
166℃
1.513
methanol: soluble5mg/mL, clear, colorless
2-8°C
8.35E-11mmHg at 25°C
Safety Information
NONH for all modes of transport
3
53
24/25
P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H413
|Warning|H315 (40%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 65 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
[10]-Gingerol Use and Manufacturing
[10]-Gingerol is a biologically active compound with anti-inflammatory and antioxidant activity
Computed Properties
Molecular Weight:350.5
XLogP3:5.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:14
Exact Mass:350.24570956
Monoisotopic Mass:350.24570956
Topological Polar Surface Area:66.8
Heavy Atom Count:25
Complexity:345
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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