Isosilybin
-
Isosilybin
structure -
-
CAS No:
72581-71-6
-
Formula:
C25H22O10
-
Chemical Name:
Isosilybin
-
Synonyms:
4H-1-Benzopyran-4-one,2-[2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-,(2R,3R)-;1,4-Benzodioxin,4H-1-benzopyran-4-one deriv.;(2R,3R)-2-[2,3-Dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one;Isosilybin;Isosilybinin;Isosilibinin
- Categories:
-
CAS No:
Description
Isosilybin (Isosilybinin) is a flavonoid from milk thistle; inhibits CYP3A4 induction with an IC50 of 74 μM.
Solid
Characteristics
155.14000
2.59
1.5±0.1 g/cm3
239-241°C
793.0±60.0 °C at 760 mmHg
274.5±26.4 °C
1.684
77.36 mg/L @ 25 °C (est)
Computed Properties
Molecular Weight:482.4
XLogP3:2.4
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:482.12129689
Monoisotopic Mass:482.12129689
Topological Polar Surface Area:155
Heavy Atom Count:35
Complexity:750
Undefined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
As a component of silymarin, it indirectly participates in the above anti-toxic effects
Learn More Other Chemicals
-
[2-[4-Methyl-2-(2-methyl-1-oxopropoxy)phenyl]-2-oxiranyl]methyl 2-methylbutanoate
22518-07-6
-
Xanthydrol
90-46-0
-
CAFFEIC ACID, 3-METHYL PHENETHYL ESTER
71835-85-3
-
Berberine Formula
2086-83-1
-
Umbelliferone Formula
93-35-6
-
Fumonisin B1 Formula
116355-83-0
-
(-)-Loganin Structure
18524-94-2
-
Bilobalide Structure
33570-04-6
-
What is BERBERINE CHLORIDE
141433-60-5
-
What is Baicalein
491-67-8
- Hot Searches
- coco3
- hclo2
- p aminobenzoic acid
- hexamethylenediamine
- epistane
- strem chemicals