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Bavachalcone

Bavachalcone structure

Bavachalcone 

structure
  • CAS No:

    28448-85-3

  • Formula:

    C20H20O4

  • Chemical Name:

    Bavachalcone

  • Synonyms:

    2-Propen-1-one,1-[2,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-,(2E)-;2-Propen-1-one,1-[2,4-dihydroxy-5-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-,(E)-;Chalcone,2′,4,4′-trihydroxy-5′-(3-methyl-2-butenyl)-,(E)-;2-Propen-1-one,1-[2,4-dihydroxy-5-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-,(2E)-;(2E)-1-[2,4-Dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one;Bavachalcone;Broussochalcone B

  • Categories:

    Biochemical Engineering  >  Chinese Herbs

Description

Bavachalcone is a major bioactive compounds isolated from Psoralea corylifolia L.; has been widely used as traditional Chinese medicine; antibiotic or anticancer agent.IC50 value:Target:Bavachalcone inhibited osteoclast formation from precursor cells with the IC(50) of approximately 1.5 microg ml(-1). The activation of MEK, ERK, and Akt by receptor activator of nuclear factor kappaB ligand (RANKL), the osteoclast differentiation factor, was prominently reduced in the presence of bavachal

Bavachalcone Basic Attributes

324.376

324.37

Characteristics

77.8

5.21

1.2±0.1 g/cm3

168-169 °C

549.6±50.0 °C at 760 mmHg

300.2±26.6 °C

1.658

1.09E-12mmHg at 25°C

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