2-(Methylthio)pyrazine
-
2-(Methylthio)pyrazine
structure -
-
CAS No:
21948-70-9
-
Formula:
C5H6N2S
-
Chemical Name:
2-(Methylthio)pyrazine
-
Synonyms:
Pyrazine,2-(methylthio)-;Pyrazine,(methylthio)-;2-(Methylthio)pyrazine;2-Methylmercaptopyrazine;Methyl pyrazinyl sulfide;(Methylthio)pyrazine;Pyrazinyl methyl sulfide;2-Methylsulfanylpyrazine;2-(Methylsulfanyl)pyrazine
- Categories:
-
CAS No:
Description
White solid Pyrazinyl methyl sulfide has an ethereal sulfureous odor
Solid|low melting white crystalline solid with an ethereal sulfurous odour
2-(Methylthio)pyrazine is an aryl sulfide.
2-(Methylthio)pyrazine Basic Attributes
126.18
126.18
878423
244-675-1
R1C97E3A4F
DTXSID1047491
2933990090
Characteristics
51.1
1.2
1.2±0.1 g/cm3
45-47.5 °C @ Solvent: Ligroine
221.2°C at 760 mmHg
87.6±21.8 °C
1.575
9533 mg/L @ 25 °C (est)|soluble in water, organic solvents, oils|very soluble (in ethanol)
0.161mmHg at 25°C
Safety Information
NONH for all modes of transport
3
22-37/38-41
22-24/25-39-26
Xn
P261-P280-P305 + P351 + P338
H302-H315-H318-H335
|Danger|H302 (88.64%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 132 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2-(Methylthio)pyrazine Use and Manufacturing
Preparation of Compound 215Step A - Synthesis of 2-BenzylpyrazineTo a solution of 2-methylsulfanyl-pyrazine (1.26 g, 10 mmol) in 15 mL THF was added benzylzinc bromide (0.5M in THF, 40 mL, 20 mmol) followed by Pd(Ph3P)4 (1.16 g, 1 mmol). The resulting reaction was heated to 60 C and allowed to stir at this temperature for 2 hours, after which time the reaction mixture was cooled to room temperature, diluted with ethyl acetate and washed with saturated sodium bicarbonate solution. The organic fraction was dried (sodium sulfate), filtered, and concentrated in vacuo to provide a crude residue which was purified using flash column chromatography (15% ethyl acetate in hexane) to provide 2- benzylpyrazine (0.76 g, 45% yield).
For daily use, food flavor
Pyrazine, 2-(methylthio)-: ACTIVE
Food additives -> Flavoring Agents|Flavoring Agents -> JECFA Flavorings Index
Flavoring Agents
Computed Properties
Molecular Weight:126.18
XLogP3:1.2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:126.02516937
Monoisotopic Mass:126.02516937
Topological Polar Surface Area:51.1
Heavy Atom Count:8
Complexity:67.4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2-(Methylthio)pyrazine
-
![China]()
CN
8 YRS
Business licensed Certified factoryManufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances ChemicalsInquiryCAS No.: 21948-70-9Grade: Food GradeContent: 99% -
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
3 YRS
Business licensedTrader Supplier of CHEMICALS,REAGENTSInquiryCAS No.: 21948-70-9Grade: Pharmaceutical GradeContent: 99%
Learn More Other Chemicals
-
B-(4-Fluoro-1-naphthalenyl)boronic acid
182344-25-8
-
Methyldopamine hydrochloride
62-32-8
-
Borago officinalis, ext.
84012-16-8
-
terphenyl Formula
26140-60-3
-
6-CHLORO-7-BENZYLPURINE Formula
1928-77-4
-
4-Methoxy-α-phenylbenzenepropanoic acid Formula
4314-68-5
-
5-Bromo-1(2H)-isoquinolinone Structure
190777-77-6
-
4-Benzylpiperidine Structure
31252-42-3
-
What is Lopinavir Intermediate 2
192726-06-0
-
What is 2,2-Dimethyl-3-phenylpropanol
13351-61-6