Ethanimidic acid, methyl ester, hydrochloride (1:1)
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Ethanimidic acid, methyl ester, hydrochloride (1:1)
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CAS No:
14777-27-6
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Formula:
C3H7NO.ClH
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Chemical Name:
Ethanimidic acid, methyl ester, hydrochloride (1:1)
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Synonyms:
Ethanimidic acid,methyl ester,hydrochloride (1:1);Acetimidic acid,methyl ester,hydrochloride;Ethanimidic acid,methyl ester,hydrochloride;Methyl acetimidate hydrochloride
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CAS No:
Ethanimidic acid, methyl ester, hydrochloride (1:1) Basic Attributes
109.55
109.029442
238-843-3
2925290090
Safety Information
UN 2811 6.1/PG 3
3
36/37/38
26-36
AK2950000
Xi
P261-P305 + P351 + P338
H315-H319-H335
Ethanimidic acid, methyl ester, hydrochloride (1:1) Use and Manufacturing
The preparation method is to pump acetonitrile, methanol, and toluene into the reactor, cool to -5~10℃, pass in dry hydrogen chloride, and maintain the salt formation temperature -5~0℃. When the calculated amount of hydrogen chloride is passed through, the Reacted at ℃ for 1h, then kept at 0-20℃ for 0.5h, and finally moved into another reaction kettle. It takes 12h for further salt formation, and the precipitated crystal is the product.
Methylacetimidate is an intermediate for the preparation of the insecticide acetamiprid. It can also be used as an intermediate for the preparation of trimethyl orthoacetate and further preparation of pyrethroids.
Computed Properties
Molecular Weight:109.55
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:109.0294416
Monoisotopic Mass:109.0294416
Topological Polar Surface Area:34.8
Heavy Atom Count:6
Complexity:42.2
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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