3-PHENOXYBENZALDEHYDE CYANOHYDRIN

The preparation method is to react 3-phenoxybenzaldehyde with potassium cyanide (or sodium cyanide) in a solvent under neutral conditions to obtain (±)α-cyano-3-phenoxybenzyl alcohol. Alpha-cyano-3-phenoxybenzyl alcohol can also be prepared by reacting the adduct obtained by reacting m-phenoxybenzaldehyde with sodium cyanosulfite with potassium cyanide, and this method has a higher yield. α-cyano-3-phenoxybenzyl alcohol is generally unstable and easy to decompose during storage. For this reason, when α-cyano-3-phenoxybenzyl alcohol is required for the preparation of pyrethroids, it is ready to use , Adopt acid chloride monoether aldehyde method, that is, chrysanthemum chloride, m-phenoxybenzaldehyde, sodium cyanide are reacted in a solvent in the presence of a phase transfer catalyst to prepare pyrethroids. During the reaction, 3-phenoxybenzaldehyde It reacts with sodium cyanide to generate cyanohydrin, and immediately reacts with chrysanthemum chloride to generate pyrethroids. The reaction is very rapid and the yield is high. At present, most industries use this method to produce pyrethroids.

Alpha-cyano-3-phenoxybenzyl alcohol is abbreviated as cyanohydrin. It is a pyrethroid insecticide such as deltamethrin, cypermethrin, cyhalothrin, fenvalerate, fenvalerate, fenvalerate, etc. Of intermediates.