 Home > Encyclopedia > Cardamonin

Cardamonin

Cardamonin structure

CAS No:
19309-14-9
Formula:
C16H14O4
Chemical Name:
Cardamonin
Synonyms:
2-Propen-1-one,1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-,(2E)-;Chalcone,2′,4′-dihydroxy-6′-methoxy-;2-Propen-1-one,1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-,(E)-;(2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one;Cardamonin;Alpinetin chalcone;Cardamomin
Categories:
Natural Products > Chalcones

Description

Cardamonin is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM.

1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one is a member of chalcones.|Cardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits to human health. Cardamonin's name comes from the fact that it can be found in cardamom spice.

Cardamonin Basic Attributes

Molecular Weight：

270.28

Exact Mass：

270.28

UNII：

H8KP1OJ8JX

HScode：

29242990

Characteristics

PSA：

66.8

XLogP3：

3.5

Appearance：

yellow

Density：

1.282±0.06 g/cm3(Predicted)

Melting Point：

203-205 °C

Boiling Point：

484.5°C at 760 mmHg

Flash Point：

182.7±22.2 °C

Refractive Index：

1.658

Water Solubility：

DMSO: ≥20mg/mL

Storage Conditions：

Store at +4°C

Safety Information

Transport codes：

UN 3077 9 / PGIII

hazard class code：

50/53

safety instructions：

61-24/25

Marks：

Precautionary statement(s)：

P273

Hazard Statements：

H400

GHS Classification：

|Warning|H400 (97.44%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]|P273, P391, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

2',4'-dihydroxy-6'-methoxychalcone

Cardamonin Use and Manufacturing

Uses

Chalone analog that display anti-inflammatory activity. Inhibits NO and PGE 2 production from LPS- and IFN- γ -induced RAW cells and inhibits TXB 2 production via the COX-1 and COX-2 pathways. Inhibits NF- κ B activation via inhibition of I κ B α degradation and phosphorylation, I κ B kinase activation and NF- κ B nuclear translocation.

Use Classification：

Polyketides [PK] -> Flavonoids [PK12] -> Chalcones and dihydrochalcones [PK1212]

Computed Properties

Molecular Weight:270.28
XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:270.08920892
Monoisotopic Mass:270.08920892
Topological Polar Surface Area:66.8
Heavy Atom Count:20
Complexity:346
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Cardamonin

Wuhan Pnq Int Trade Co., Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Apigenin,PQQ,NMNH

High Quality Cardamom Extract Powder CAS 19309-14-9 98% Cardamonin Competitive Price

CAS No.: 19309-14-9

Grade: Chemical Grade

Content: 99%

Inquiry
Cuicheng Biomedical Technology Contact Supplier

CN
1 YR

Business licensed Certified factory

Manufactory Supplier of Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5,Ginsenoside Rg5,Ginsenoside Rh2,Protopanaxatriol,Epmedin C,Icariin,Icaritin,Baohuoside I,Total Ginsenosides,Total Ginsenosides from Ginseng Stems And Leaves,Oridonin,Oleuropein,Curcumin,(20)-Ginsenoside Rg3,(20)-Protopanaxadiol

CARDAMONIN

Unit Price: $3400-3500 /G EXW

CAS No.: 19309-14-9

Grade: Industrial Grade

Content: 98%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

CARDAMONIN 99% white powder kanbei

CAS No.: 19309-14-9

Grade: Industrial Grade

Content: 99%

Inquiry

Learn More Other Chemicals

Hesperidin methylchalcone

24292-52-2
Trilobatin 2''-acetate

647853-82-5
3'-Methyl-4-O-Methylhelichrysetin

109471-13-8
2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone Formula

75679-58-2
3,2′,4′-Trihydroxy-4-methoxychalcone Formula

13323-67-6
Ethyllucidone Formula

1195233-59-0
Calyxin B Structure

164991-53-1
2',4'-Dihydroxy-2,3',6'-trimethoxychalcone Structure

100079-39-8
What is 246TRIHYDROXYCHALCONE

4197-97-1
What is methyllinderone

3984-73-4

Hot Searches: retatrutida price; lithium hydrozide; price of ammonium nitrate fertilizer; price of graphite; solvent naphtha suppliers; dhafor

Guide of Cardamonin

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Learn More Other Chemicals

Cardamonin

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.