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Metaflumizone

Metaflumizone structure

CAS No:
139968-49-3
Formula:
C24H16F6N4O2
Chemical Name:
Metaflumizone
Synonyms:
Hydrazinecarboxamide,2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]-;2-[2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]hydrazinecarboxamide;Metaflumizone;BAS 320I;BAS 320021;BASF 320;BAS 320;NNI 0250;Alverde;BAS 32001;Altrevin;BAS 3201;ProMeris;875656-67-0
Categories:
Chemical Reagents > Organic Reagents

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Description

Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker[1].

Metaflumizone Basic Attributes

Molecular Weight：

506.404

Exact Mass：

506.40

EC Number：

604-167-6

UNII：

COL1OR95DS

DSSTox ID：

DTXSID6040373

ATC Code：

QP53AX25|QP53AD51

Characteristics

PSA：

86.51000

XLogP3：

6.05

Density：

1.3±0.1 g/cm3

Refractive Index：

1.547

Safety Information

Transport codes：

UN 3077 9 / PGIII

RTECS Number：

MV1576452

Precautionary statement(s)：

P273

Hazard Statements：

H400

GHS Classification：

|Warning|H361 (41.59%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]|P201, P202, P260, P263, P264, P270, P273, P281, P308+P313, P314, P391, P405, and P501|Aggregated GHS information provided by 215 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Drug Indication：

Treatment and prevention of flea infestations (Ctenocephalides canis and C. felis) in cats. The veterinary medicinal product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).|For the treatment and prevention of infestations by fleas (Ctenocephalides canis and C. felis), and ticks (Ixodes ricinus, Ixodes hexagonus, Rhipicephalus sanguineus, Dermacentor reticulatus and Dermacentor variabilis), and treatment of demodicosis (caused by Demodex spp.) and lice (Trichodectes canis) in dogs.The veterinary medicinal product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).

MeSH Entry Terms：

metaflumizone

Metaflumizone Use and Manufacturing

Uses

Metaflumizone is a semicarbazone insecticide that works by blocking sodium channel in target insects resulting in paralyzation associated with blocking nerve activity. Metaflumizone is useful as a heartworm control treatment.

Use Classification：

Agrochemicals -> Insecticides|Veterinary drugs -> ProMeris -> EMA Drug Category|Ectoparasiticides for topical use, incl. insecticides -> Veterinary pharmacotherapeutic group|Veterinary drugs -> ProMeris Duo -> EMA Drug Category

Computed Properties

Molecular Weight:506.4
XLogP3:6.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:506.11774474
Monoisotopic Mass:506.11774474
Topological Polar Surface Area:86.5
Heavy Atom Count:36
Complexity:806
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Metaflumizone

CAS No.: 139968-49-3

Content: 99.00%

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