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Home > Encyclopedia > PENTA(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE

PENTA(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE

PENTA(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE structure

PENTA(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE 

structure
  • CAS No:

    41024-91-3

  • Formula:

    C24H34O10S2

  • Chemical Name:

    PENTA(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE

  • Synonyms:

    PENTA(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE;PENTAETHYLENE GLYCOL DI-P-TOLUENESULPHONATE;PENTA(ETHYLENE GLYCOL)DI-P-TOSYLATE;PENTAETHYLENE GLYCOL DITOSYLATE;3,6,9,12-TETRAOXATETRADECANE-1,14-DIYL DITOSYLATE;Pentaethylene glycol di-p-tosylate~3,6,9,12-Tetraoxatetradecane-1,14-diyl di-p-toluenesulphonate;3,6,9,12-tetraoxatetradecane-1,14-diyl di-p-toluenesulfonate;NSC625453

  • Categories:

    Chemical Reagents  >  Organic Reagents

Description

Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PENTA(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE Basic Attributes

546.65

546.15900

3599245

625453

2909499000

Characteristics

140

2.3

1.26

661.4°C at 760 mmHg

>230 °F

n20/D 1.524(lit.)

Not miscible or difficult to mix in water.

Safety Information

NONH for all modes of transport

3

36/37/38

26-36

Xi

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

PENTA(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE Use and Manufacturing

Methods of Manufacturing

Triglycol dichloride (10.8g, 57.8mmol) was added to a stirred mixture of KOH (7.8g, 139.3mmol) in ethylene glycol (60mL) at room temperature under N

Uses

Used to prepare calix[4]arenes,1 calix[5]arenes,2 and crown ethers.3

Computed Properties

Molecular Weight:546.7
XLogP3:2.3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:19
Exact Mass:546.15933962
Monoisotopic Mass:546.15933962
Topological Polar Surface Area:140
Heavy Atom Count:36
Complexity:694
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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