8-Quinolinesulfonyl chloride
-
8-Quinolinesulfonyl chloride
structure -
-
CAS No:
18704-37-5
-
Formula:
C9H6ClNO2S
-
Chemical Name:
8-Quinolinesulfonyl chloride
-
Synonyms:
8-Quinolinesulfonyl chloride;8-Chlorosulfonyl-1-benzazine;8-Quinolylsulfonyl chloride;Quinoline-8-sulfonic acid chloride;8-Quinolinylsulfonyl chloride;8-Chinolinsulfonyl chloride;NSC 91506;8-Chlorosulfonylquinoline;2361319-59-5
- Categories:
-
CAS No:
8-Quinolinesulfonyl chloride Basic Attributes
227.67
227.67
156347
242-515-5
5ZIK3TJS9M
91506
DTXSID90171975
29334990
Characteristics
55.4
1.9
white to light yellow crystal powder
1.483±0.06 g/cm3(Predicted)
124-126 °C
306°C
306°C
1.647
methanol: soluble10mg/mL, clear, colorless to light yellow
2-8°C
0.012mmHg at 25°C
Safety Information
III
8
UN 3261 8/PG 2
3
34
26-36/37/39-45-27
VC2830000
C
P280-P305 + P351 + P338-P310
H314
|Danger|H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501|Aggregated GHS information provided by 45 companies from 3 notifications to the ECHA C&L Inventory.
8-Quinolinesulfonyl chloride Use and Manufacturing
Chlorosulfonic acid (6.0 gram, 51.5 mmole) was charged into a container equipped with a magnetic stirrer. While stirring under nitrogen stream, quinoline (Compound 7) (1.0 g, 7.74 mmol) was added into the container under ice-cooling. While stirring, the temperature of the container was raised to 140°C and reaction was allowed to proceed at the same temperature for 10 hours. Then, the temperature was reduced to 40°C, and thionyl chloride (2.0 g, 16.0 mmole) was added. While stirring, the temperature was raised to 70°C, allowed the reaction to proceed at the same temperature for 4 hours. After the reaction was completed, let the temperature returned to room temperature, then poured into ice-water, solid precipitate appeared immediately, stirred the mixture for 30 minutes, and then filtered, dried by vacuo, 1.7 g Compound 9 (yield: 99percent) was obtained. m/z:228.0 (M+1).
Coupling agent in oligonucleotide synthesis; olefins are formed from secondary esters at moderate temperatures.
Computed Properties
Molecular Weight:227.67
XLogP3:1.9
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:226.9807773
Monoisotopic Mass:226.9807773
Topological Polar Surface Area:55.4
Heavy Atom Count:14
Complexity:298
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 8-Quinolinesulfonyl chloride
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
2 YRS
Business licensedTrader Supplier of pharmaceutical intermediates,excipients,plant extracts,food additives,CDMO,fine cheimcals,Octadecanedioic acid,Eicosanedioic AcidInquiryCAS No.: 18704-37-5Grade: Pharmaceutical GradeContent: 99%
Learn More Other Chemicals
-
1,3,5-Cycloheptatriene-1-carbonyl chloride (9CI)
103533-75-1
-
3'-De(diMethylaMino)-3'-[[(2-Methoxyethoxy)Methyl]diMethylaMMonio]erythroMycin 9-OxiMe Chloride
151750-47-9
-
decoxymethyl-dimethyl-octyl-azanium chloride
366491-03-4
-
4-[3-(3,5-DICHLORO-PHENYL)-UREIDO]-BENZENESULFONYL CHLORIDE Formula
677326-84-0
-
2,5-DICHLOROBENZYLZINC CHLORIDE Formula
737797-20-5
-
2,5-DIBROMO-3,6-DIFLUOROBENZENESULFONYL CHLORIDE Formula
207853-66-5
-
Dibenzofuran-3-sulfonyl chloride Structure
42138-14-7
-
2,4-Dibromo-5-fluorobenzenesulfonyl chloride Structure
1000578-09-5
-
What is Selenium(I) chloride (99%-Se)
21317-32-8
-
What is 2,6-dibromo-4-methylbenzene-1-sulfonyl chloride
73732-31-7