α-Apooxytetracycline
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α-Apooxytetracycline
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CAS No:
18695-01-7
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Formula:
C22H22N2O8
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Chemical Name:
α-Apooxytetracycline
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Synonyms:
1-Cyclohexene-1-carboxamide,4-[(1R)-1,3-dihydro-4,5-dihydroxy-9-methyl-3-oxonaphtho[2,3-c]furan-1-yl]-3-(dimethylamino)-2,5-dihydroxy-6-oxo-,(3S,4S,5S)-;(3S,4S,5S)-4-[(1R)-1,3-Dihydro-4,5-dihydroxy-9-methyl-3-oxonaphtho[2,3-c]furan-1-yl]-3-(dimethylamino)-2,5-dihydroxy-6-oxo-1-cyclohexene-1-carboxamide;α-Apooxytetracycline;α-Apoterramycin;1361013-47-9
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CAS No:
Characteristics
171
1.25860
Khaki Crystalline Powder
1.62±0.1 g/cm3(Predicted)
200°C
742.4±60.0 °C(Predicted)
347.195ºC
Refrigerator, Under Inert Atmosphere
α-Apooxytetracycline Use and Manufacturing
α-Apooxytetracycline is a degradation product of oxytetracycline, formed under acidic conditions. After initial dehydration to anhydrooxytetracycline, it undergoes an internal cyclisation of the C5-OH to the C12 ketone. The resulting cleavage of the C12-C12a bond generates two isomers, α- and β-apooxytetracycline. α-Apooxytetracycline is an important standard for monitoring oxytetracycline stability.
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