 Home > Encyclopedia > IAEDANS

IAEDANS

IAEDANS structure

CAS No:
36930-63-9
Formula:
C14H15IN2O4S
Chemical Name:
IAEDANS
Synonyms:
1-Naphthalenesulfonic acid,5-[[2-[(2-iodoacetyl)amino]ethyl]amino]-;1-Naphthalenesulfonic acid,5-[[2-[(iodoacetyl)amino]ethyl]amino]-;5-[[2-[(2-Iodoacetyl)amino]ethyl]amino]-1-naphthalenesulfonic acid;N-(Iodoacetamidoethyl)-1-aminonaphthalene-5-sulfonic acid;N-[2-(Iodoacetylamino)ethyl]-5-naphthylamine-1-sulfonic acid;N-Iodoacetyl-N′-(5-sulfo-1-naphthyl)ethylenediamine;N-(Iodoacetamidoethyl)-5-naphthylamine-1-sulfonic acid;N-Iodoacetylaminoethyl-5-naphthylamine-1-sulfonic acid;5-(Iodoacetamidoethyl)aminonaphthalene-1-sulfonic acid;1,5-IAEDANS;N-(Iodoacetyl)-N′-(1-sulfo-5-naphthyl)ethylenediamine;IEDANS;NSC 328384;IAEDANS;5-[[[(2-Iodoacetyl)amino]ethyl]amino]naphthalene-1-sulfonic acid;N-Iodoacetyl-N-(5-sulfo-1-naphthyl)ethylenediamine;1-Naphthalenesulfonic acid,5-[(2-aminoethyl)(iodoacetyl)amino]-;59862-96-3;119056-53-0
Categories:
Chemical Reagents > Organic Reagents

Description

Yellow Powder

5-{[2-(iodoacetamido)ethyl]amino}naphthalene-1-sulfonic acid is an aminonaphthalenesulfonic acid fluorophore with a structure consisting of ethylenediamine substituted on the nitrogens with iodoacetyl and 5-sulfonyl-1-naphthyl groups. It has a role as a fluorescent probe.

IAEDANS Basic Attributes

Molecular Weight：

434.25

Exact Mass：

434.25

EC Number：

253-277-7

UNII：

6V7G304M5M

NSC Number：

328384

DSSTox ID：

DTXSID10190421

HScode：

2924299090

Characteristics

PSA：

104

XLogP3：

3.59430

Appearance：

yellow crystalline

Density：

1.808 g/cm3

Melting Point：

300 °C

Refractive Index：

1.707

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38

safety instructions：

22-24/25

Marks：

Stability/Shelf Life：

Sensitive to Light

Precautionary statement(s)：

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H315

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

MeSH：

Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags. (See all compounds classified as Fluorescent Dyes.)

MeSH Entry Terms：

1,5-I-AEDANS

IAEDANS Use and Manufacturing

A fluorescent sulfhydryl reagent which is sensitive to photo catalyzed degradation in both aqueous solution and organic solvents.It readily reacts with both thiol compounds and sulfhydryl groups to provide photo stable covalent derivatives.Fluorescence:max. Abs. l = 336nm, max. Em. l = 490 nm.

Computed Properties

Molecular Weight:434.25
XLogP3:1.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:433.97973
Monoisotopic Mass:433.97973
Topological Polar Surface Area:104
Heavy Atom Count:22
Complexity:480
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes