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Chlorproguanil

Chlorproguanil structure

CAS No:
537-21-3
Formula:
C11H15Cl2N5
Chemical Name:
Chlorproguanil
Synonyms:
Imidodicarbonimidic diamide,N-(3,4-dichlorophenyl)-N′-(1-methylethyl)-;Biguanide,1-(3,4-dichlorophenyl)-5-isopropyl-;N-(3,4-Dichlorophenyl)-N′-(1-methylethyl)imidodicarbonimidic diamide;M 5943;Chlorproguanil;1-(3,4-Dichlorophenyl)-5-isopropylbiguanide;N1-3,4-Dichlorophenyl-N5-isopropylbiguanide;N1-3,4-Dichlorophenyl-N5-isopropyldiguanide
Categories:
Chemical Reagents > Organic Reagents

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Chlorproguanil Basic Attributes

Molecular Weight：

290.19

Exact Mass：

288.18

EC Number：

208-660-3

DSSTox ID：

DTXSID5022807

Characteristics

PSA：

88.8

XLogP3：

Density：

1.40±0.1 g/cm3(Predicted)

Melting Point：

120-121 °C

Drug Information

MeSH：

Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585) (See all compounds classified as Antimalarials.)

Metabolism/Metabolites：

1-[Amino-(3,4-dichloroanilino)methylidene]-2-propan-2-ylguanidine has known human metabolites that include 1-[amino-(3,4-dichloroanilino)methylidene]-2-(2-hydroxypropan-2-yl)guanidine.

MeSH Entry Terms：

chlorproguanil

Chlorproguanil Use and Manufacturing

An antimalarial agent used in combination with Dapsone (D193250).

Computed Properties

Molecular Weight:288.17
XLogP3:3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:287.0704509
Monoisotopic Mass:287.0704509
Topological Polar Surface Area:88.8
Heavy Atom Count:18
Complexity:329
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes