Carbazochrome sodium sulfonate
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Carbazochrome sodium sulfonate
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CAS No:
51460-26-5
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Formula:
C10H12N4O5S.Na
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Chemical Name:
Carbazochrome sodium sulfonate
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Synonyms:
1H-Indole-2-sulfonic acid,5-[2-(aminocarbonyl)hydrazinylidene]-2,3,5,6-tetrahydro-1-methyl-6-oxo-,sodium salt (1:1);1H-Indole-2-sulfonic acid,5-[(aminocarbonyl)hydrazono]-2,3,5,6-tetrahydro-1-methyl-6-oxo-,monosodium salt;2-Indolinesulfonic acid,5,6-dihydro-1-methyl-5,6-dioxo-,5-semicarbazone,sodium salt;Adrenochrome sulfonate Ac 17;Carbazochrome sodium sulfonate;Adona;AC 17;Carbazon;Adenaron;Donaseven;Tazin;Odanon;Emex
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CAS No:
Description
Carbazochrome(AC-17) is an antihemorrhagic agent.Target: OthersCarbazochrome is an antihemorrhagic agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. It is hoped that this drug can be used in the future for preventing excessive blood flow during surgical operations and the treatment of hemorrhoids. Carbazochrome interacts with α-adrenoreceptors on surface of platelets, which ar
Carbazochrome sodium sulfonate Basic Attributes
376.32
322.03478492
257-217-0
DTXSID9022732|DTXSID40873058
2933990090
Characteristics
227-228 °C (decomp)
Oral-mouse LD50:>10000 mg/kg; intravenous-mouse LD50:>600 mg/kg
Flammable; burning releases toxic nitrogen oxide, sodium oxide and sulfur oxide fumes
Safety Information
2989
R22:Harmful if swallowed. R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
S22:Do not breathe dust . S61:Avoid release to the environment. Refer to special instructions safety data sheet .
Xn
Treasury is ventilated, low temperature and dry; stored separately from food materials
Drug Information
Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure. (See all compounds classified as Hemostatics.)
AC-17
Carbazochrome sodium sulfonate Use and Manufacturing
Carbazochrome is an antihemorrhagic for use in the treatment of hemorrhoids.
Computed Properties
Molecular Weight:322.28
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:322.03478492
Monoisotopic Mass:322.03478492
Topological Polar Surface Area:157
Heavy Atom Count:21
Complexity:522
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
This product can reduce capillary permeability, enhance the retraction effect of broken capillary ends, and increase the resistance of capillaries to damage. It is often used for various types of bleeding caused by increased capillary permeability.
Registered Holders
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Ningbo Naive Pharmaceutical Co., Ltd.
Active
China
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Hainan Huluwa Pharmaceutical Group Co., Ltd.
Active
China
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Hubei Hongyuan Pharmaceutical Technology Co., Ltd.
Active
China
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