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Home > Encyclopedia > (11α,16α)-16,17-Epoxy-11-hydroxypregn-4-ene-3,20-dione

(11α,16α)-16,17-Epoxy-11-hydroxypregn-4-ene-3,20-dione

(11α,16α)-16,17-Epoxy-11-hydroxypregn-4-ene-3,20-dione structure

(11α,16α)-16,17-Epoxy-11-hydroxypregn-4-ene-3,20-dione 

structure
  • CAS No:

    19427-36-2

  • Formula:

    C21H28O4

  • Chemical Name:

    (11α,16α)-16,17-Epoxy-11-hydroxypregn-4-ene-3,20-dione

  • Synonyms:

    Pregn-4-ene-3,20-dione,16,17-epoxy-11-hydroxy-,(11α,16α)-;Pregn-4-ene-3,20-dione,16α,17-epoxy-11α-hydroxy-;Progesterone,16α,17-epoxy-11α-hydroxy-;(11α,16α)-16,17-Epoxy-11-hydroxypregn-4-ene-3,20-dione;11α-Hydroxy-16α,17α-epoxypregn-4-ene-3,20-dione;11α-Hydroxy-16α,17α-oxidoprogesterone;16α,17-Epoxy-11α-hydroxypregn-4-ene-3,20-dione;11α-Hydroxy-16α,17-epoxyprogesterone

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Off-White Solid

(11α,16α)-16,17-Epoxy-11-hydroxypregn-4-ene-3,20-dione Basic Attributes

344.44

344.44

243-049-5

Characteristics

66.90000

1.25

1.25±0.1 g/cm3(Predicted)

238.0-238.5 °C @ Solvent: Benzene, Cyclohexane

508.7±50.0 °C(Predicted)

178.7±23.6 °C

1.586

0mmHg at 25°C

(11α,16α)-16,17-Epoxy-11-hydroxypregn-4-ene-3,20-dione Use and Manufacturing

Methods of Manufacturing

The product can be prepared through the steps of ring opening, acetylation, oxidation, hydrolysis, elimination, epoxidation, oxidation and other steps.

Uses

11α-Hydroxy-16,17α-epoxyprogesterone is a steroid hormone. an analog of Progesterone (P755900), a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.

Computed Properties

Molecular Weight:344.4
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:344.19875937
Monoisotopic Mass:344.19875937
Topological Polar Surface Area:66.9
Heavy Atom Count:25
Complexity:711
Undefined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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