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Alcuronium

Alcuronium structure

CAS No:
23214-96-2
Formula:
C44H50N4O2
Chemical Name:
Alcuronium
Synonyms:
10H,21H-1,21:10,12-Diethano-19aH,20bH-dipyrrolo[3,2-f:3′,2′-f′][1,5]diazocino[3,2,1-jk:7,6,5-j'k′]dicarbazolium,2,3,11,11a,13,14,22,22a-octahydro-23,26-bis(2-hydroxyethylidene)-1,12-di-2-propen-1-yl-,(1R,3aS,10S,11aS,12R,14aS,19aS,20bS,21S,22aS,23E,26E)-;Nortoxiferinium,N,N′-diallyl-;Toxiferine I,4,4′-didemethyl-4,4′-di-2-propenyl-;10H,21H-1,21:10,12-Diethano-19aH,20bH-dipyrrolo[3,2-f:3′,2′-f′][1,5]diazocino[3,2,1-jk:7,6,5-j'k′]dicarbazolium,2,3,11,11a,13,14,22,22a-octahydro-23,26-bis(2-hydroxyethylidene)-1,12-di-2-propenyl-,(1R,3aS,10S,11aS,12R,14aS,19aS,20bS,21S,22aS,23E,26E)-;(1R,3aS,10S,11aS,12R,14aS,19aS,20bS,21S,22aS,23E,26E)-2,3,11,11a,13,14,22,22a-Octahydro-23,26-bis(2-hydroxyethylidene)-1,12-di-2-propen-1-yl-10H,21H-1,21:10,12-diethano-19aH,20bH-dipyrrolo[3,2-f:3′,2′-f′][1,5]diazocino[3,2,1-jk:7,6,5-j'k′]dicarbazolium;Alcuronium;Diallylnortoxiferine;N,N′-Diallylnortoxiferinium;4,4′-Didemethyl-4,4′-dipropenyltoxiferine I;10H,21H-1,21:10,12-Diethano-19aH,20bH-dipyrrolo[3,2-f:3′,2′-f′][1,5]diazocino[3,2,1-jk:7,6,5-j'k′]dicarbazolium,2,3,11,11a,13,14,22,22a-octahydro-23,26-bis(2-hydroxyethylidene)-1,12-di-2-propenyl-,[1R-(1α,3aS*,10α,11aβ,12α,14aS*,19aα,20bα,21α,22aβ,23E,26E)]-;Diallyltoxiferine;35-59-6;19289-69-1;33392-75-5
Categories:
Organic Chemistry > Amides

Description

ChEBI: An indole alkaloid of the curare family. A neuroblocker, it is often used in chloride form as an anesthesia adjuvant.

Alcuronium is an indole alkaloid of the curare family. A neuroblocker, it is often used in chloride form as an anesthesia adjuvant. It has a role as a muscle relaxant.|A non-depolarizing skeletal muscle relaxant similar to [tubocurarine]. It is used as an anesthesia adjuvant.|A non-depolarizing skeletal muscle relaxant similar to TUBOCURARINE. It is used as an anesthesia adjuvant.

Alcuronium Basic Attributes

Molecular Weight：

666.905

Exact Mass：

666.393

UNII：

S8U3J5W06N

DSSTox ID：

DTXSID8048234

ATC Code：

M - Musculo-skeletal system

Characteristics

PSA：

46.9

XLogP3：

3.1

Drug Information

MeSH：

Agents that are administered in association with anesthetics to increase effectiveness, improve delivery, or decrease required dosage. (See all compounds classified as Adjuvants, Anesthesia.)|Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarization of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvants. (See all compounds classified as Neuromuscular Nondepolarizing Agents.)|Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses. (See all compounds classified as Nicotinic Antagonists.)

MeSH Entry Terms：

Alcuronium

Computed Properties

Molecular Weight:666.9
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:666.39337685
Monoisotopic Mass:666.39337685
Topological Polar Surface Area:46.9
Heavy Atom Count:50
Formal Charge:2
Complexity:1510
Defined Atom Stereocenter Count:10
Defined Bond Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes