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Home > Encyclopedia > ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL

ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL

ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL structure

ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL 

structure
  • CAS No:

    10129-56-3

  • Formula:

    C8H8Cl3NO

  • Chemical Name:

    ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL

  • Synonyms:

    PETCM;APOPTOSIS ACTIVATOR I;ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL;1-(4-PYRIDYL)-2-HYDROXY-3,3,3-TRICHLOROPROPANE;1,1,1-TRICHLORO-3-(4-PYRIDYL)PROPAN-2-OL;a-(Trichloromethyl)-4-pyridineethanol;α-(Trichloromethyl)-4-pyridineethanol,1-(4-Pyridyl)-2-hydroxy-3,3,3-trichloropropane;α-(Trichloromethyl)-4-pyridineethanol

Description

PETCM is an activator of caspase-3. PETCM can induces cell apoptosis and stimulate apoptosome formation in HeLa cell cytosols[1].


1,1,1-trichloro-3-pyridin-4-yl-2-propanol is a member of pyridines.

ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL Basic Attributes

240.51

238.96700

13699

DTXSID00279678

2933399090

Characteristics

33.1

2.35520

solid

1.465±0.06 g/cm3(Predicted)

342.2±37.0 °C(Predicted)

160.8ºC

1.579

DMSO: 22 mg/mL, soluble

Store at RT

Safety Information

3

22

36

Xn

P264, P270, P301+P312, P330, P501

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

alpha-(trichloromethyl)-4-pyridineethanol

Computed Properties

Molecular Weight:240.5
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:238.967147
Monoisotopic Mass:238.967147
Topological Polar Surface Area:33.1
Heavy Atom Count:13
Complexity:154
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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