PGD3
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PGD3
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CAS No:
71902-47-1
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Formula:
C20H30O5
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Chemical Name:
PGD3
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Synonyms:
Prosta-5,13,17-trien-1-oic acid,9,15-dihydroxy-11-oxo-,(5Z,9α,13E,15S,17Z)-;(5Z,9α,13E,15S,17Z)-9,15-Dihydroxy-11-oxoprosta-5,13,17-trien-1-oic acid;Prostaglandin D3;PGD3
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CAS No:
Description
ChEBI: A member of the class of prostaglandins D that is prosta-5,13,17-trien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,13E,15S,17Z-st reoisomer).
Solid
Prostaglandin D3 is a member of the class of prostaglandins D that is prosta-5,13,17-trien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,13E,15S,17Z-stereoisomer). It has a role as a human metabolite. It is a conjugate acid of a prostaglandin D3(1-).
PGD3 Use and Manufacturing
Prostaglandin D3 (PGD3) is produced by the metabolism of EPA via the COX pathway. It is equipotent to PGD2 in decreasing systemic blood pressure in rats and in decreasing intraocular pressure in rabbits. However, it is 3-5 times more potent than PGD2 in the inhibition of ADP-induced human platelet aggregation.[Cayman Chemical]
Fatty Acyls [FA] -> Eicosanoids [FA03] -> Prostaglandins [FA0301]
Computed Properties
Molecular Weight:350.4
XLogP3:2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:11
Exact Mass:350.20932405
Monoisotopic Mass:350.20932405
Topological Polar Surface Area:94.8
Heavy Atom Count:25
Complexity:506
Defined Atom Stereocenter Count:4
Defined Bond Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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