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Amidephrine

Amidephrine structure

CAS No:
37571-84-9
Formula:
C10H16N2O3S
Chemical Name:
Amidephrine
Synonyms:
Methanesulfonamide,N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]-;Methanesulfonamide,N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]-,(±)-;N-[3-[1-Hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide;(±)-Amidephrine;Amidephrine;MJ 1996;Amidefrine;3354-67-4;53562-74-6
Categories:
Organic Chemistry > Amides

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Description

Amidefrine is a sulfonamide.

Amidephrine Basic Attributes

Molecular Weight：

244.31064

Exact Mass：

244.31

UNII：

NI24N176MY|U56LDN9FFT

Characteristics

PSA：

86.8

XLogP3：

-1

Density：

1.311±0.06 g/cm3(Predicted)

Melting Point：

159-161 °C

Drug Information

MeSH：

Drugs that selectively bind to and activate alpha adrenergic receptors. (See all compounds classified as Adrenergic alpha-Agonists.)

MeSH Entry Terms：

3-(2-methylamino-1-hydroxyethyl)methanesulfonanilide

Amidephrine Use and Manufacturing

Amidephrine is an alpha-adrenergic agonist. Amidephrine was shown to produce non-selective, dose-dependent increase in IUP and BP and decrease in heart rate in anesthetized micropig and rabbit

Computed Properties

Molecular Weight:244.31
XLogP3:-1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:244.08816355
Monoisotopic Mass:244.08816355
Topological Polar Surface Area:86.8
Heavy Atom Count:16
Complexity:300
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes