N,N-Dimethyl-1,3-propanediamine

102.18

102.18

605293

203-680-9

I98I2UEC03

1227

1067

2734|1993

DTXSID5025102

Colorless liquid

29212900

29.26000

-0.29

Clear Liquid

0.8100 g/cm³ @ Temp: 30 °C

-70 °C

123 °C

90 °F

1.434-1.436

H2O: soluble

Flammables area

5 mm Hg ( 20 °C)

3.6 (vs air)

Oral-rat LD50: 1870 mg/kg

Flammable; burning produces toxic nitrogen oxide fumes

2.3-12.35%(V)

Ammoniacal odor

Sets to a glass below freezing point of -70 °C

Highly flammable. Temperature sensitive and possibly sensitive to air. Water soluble.

Amines, Phosphines, and Pyridines

Highly Flammable

DIMETHYLAMINOPROPYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

35.6 kJ/mol

II

8

UN 2733 3/PG 3

2

10-22-34-43-21/22

26-36/37/39-45

TX7525000

C

The warehouse is ventilated, low temperature and dry; stored and transported separately from oxidants and acids

Stable under normal temperatures and pressures.

P210-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P333 + P313-P403 + P235

H226-H302 + H312-H314-H317-H335

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Ignites on contact with cellulose nitrate of high surface area.|Reaction with 1,2-dichloroethane produces explosive acetylene gas.

This compound is flammable. (NTP, 1992)|Flammable. Gives off irritating or toxic fumes (or gases) in a fire. Above 35 °C explosive vapour/air mixtures may be formed.|Flammable - 3rd degree

|Danger|H226: Flammable liquid and vapor [Warning Flammable liquids]|P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P272, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P333+P313, P363, P370+P378, P403+P235, P405, and P501|H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]|P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P333+P313, P363, P370+P378, P403+P233, P403+P235, P405, and P501|Aggregated GHS information provided by 1341 companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P314, P321, P322, P330, P333+P313, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501

Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)

RECOMMENDED RESPIRATOR: When working with this chemical, wear a NIOSH-approved full face chemical cartridge respirator equipped with the appropriate organic vapor cartridges. If that is not available, a half face respirator similarly equipped plus airtight goggles can be substituted. However, please note that half face respirators provide a substantially lower level of protection than do full face respirators. RECOMMENDED GLOVE MATERIALS: It is recommended that two different glove types be used for best protection. However, if this chemical makes direct contact with your gloves, or if a tear, puncture or hole develops, remove them at once. SUGGESTED GLOVES: Butyl rubber (NTP, 1992)|... B) PROTECT HANDS WITH RUBBER GLOVES ... /ALIPHATIC AMINES/

FLAMMABLE, MODERATE FIRE RISK.|Very flammable when exposed to heat, flame, or oxidizers.

Explosive limits , vol% in air: 2.3-12.3

To fight fire, use alcohol foam, carbon dioxide, dry chemical.

A) PREVENT CONTACT WITH ALIPHATIC AMINES ... PROCESS THEM IN CLOSED VESSELS. B) ... USE SUITABLE BARRIER CREAMS /ON HANDS/. C) DECR CONCN OF ... VAPORS BY GOOD VENTILATION ... AMINES WITH HEAVY VAPORS ... SHOULD BE DRAWN OFF BY DESCENT. /ALIPHATIC AMINES/|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

A skin and eye irritant.

Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water. Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment.

Fireproof. Separated from strong oxidants, strong acids and food and feedstuffs. Well closed.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema. Medical observation is indicated.

Repeated or prolonged contact may cause skin sensitization.

NO open flames, NO sparks and NO smoking. Above 35 °C use a closed system, ventilation and explosion-proof electrical equipment.

AVOID ALL CONTACT!

Use ventilation, local exhaust or breathing protection.

Protective gloves. Protective clothing.

Wear face shield or eye protection in combination with breathing protection.

| 3 - Materials that, under emergency conditions, can cause serious or permanent injury.| 2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air.| 0 - Materials that in themselves are normally stable, even under fire conditions.

moderately toxic

LD50 Rabbit skin 600 ul/kg

SYMPTOMS: Symptoms of exposure to this compound include strong local irritation of tissue, lacrimation. ACUTE/CHRONIC HAZARDS: Toxic. Causes strong irritation on contact. Lachrymator. Dangerous fire hazard. When heated to decomposition, emits toxic fumes. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Fresh air, rest. Half-upright position. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

... VAPOR HAS CAUSED CORNEAL DISTURBANCE & BLURRED VISION. WORKERS EXPOSED TO CONCN THOUGHT TO BE ABOUT 30 PPM IN AIR NOTED DURING SEVERAL DAYS THAT VISION BECAME BLURRED TOWARD END OF WORK DAY, SOMETIMES WITH APPEARANCE OF HALOES AROUND LIGHTS, PAIN, PHOTOPHOBIA & HEADACHE, USUALLY BETTER BY NEXT DAY.|IN THREE WORKERS WHO HAD SYMPTOMS PERSISTING TWO TO THREE DAYS AFTER EXPOSURE, THE CORNEAL EPITHELIUM WAS SEEN TO BE EDEMATOUS, BUT NO OTHER OCULAR ABNORMALITIES WERE OBSERVED.|DURING 1974 A GROUP OF 25 WORKERS WERE EXPOSED TO AN EPOXY RESIN SYSTEM IN MOLD ROOM OF SKI MFR PLANT. 3-DIMETHYLAMINO PROPYLAMINE (3-DMAPA) WAS ONLY VOLATILIZED SUBSTANCE. ASSEMBLERS (A SUBGROUP) IN HIGHEST BREATHING ZONE (0.9 PPM) HAD HIGHEST PREVELANCE OF SYMPTOMS & SIGNIFICANT DECR IN LUNG FUNCTION OVER WORKSHIFT. EXTENSIVE IMPROVEMENTS IN LOCAL VENTILATION REDUCED AVG BREATHING ZONE EXPOSURE TO NEARLY 1/7 OF CONCN. CROSS-SECTIONAL STUDY IN 1977 SHOWED THAT AT THIS LEVEL THERE WAS MARKED REDUCTION IN SYMPTOMS & EXPIRATORY FUNCTION OF ASSEMBLERS NO LONGER DECR OVER WORKSHIFT. LONGITUDINAL COMPARISON OF LUNG FUNCTION OF WORKERS EXPOSED MORE THAN 2 YR SHOWED EVIDENCE OF DECR FROM 1975 TO 1977, BUT NONE FROM 1977 TO 1978.|TOXIC BY INGESTION & INHALATION, STRONG IRRITANT.|For more Human Toxicity Excerpts (Complete) data for N,N-DIMETHYL-1,3-PROPANEDIAMINE (8 total), please visit the HSDB record page.

3-(dimethylamino)-1-propylamine

The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

Sore throat. Cough. Burning sensation. Shortness of breath. Laboured breathing. Symptoms may be delayed.

Pain. Redness. Serious skin burns.

Pain. Blurred vision. Severe deep burns.

Agriculture, forestry, fishing and hunting|1,3-Propanediamine, N1,N1-dimethyl-: ACTIVE|ANTITHROMBOGENIC MATERIAL IS PRODUCED BY TREATING POLYAMIDES WITH NONSYMMETRIC ALKYLDIAMINES, FOLLOWED BY QUATERNIZATION WITH ALKYL HALIDES & TREATMENT WITH ANIONIC ANTITHROMBOGENIC COMPOUNDS. PRODUCT IS SUITABLE FOR MAKING SURGICAL PROSTHETICS.|HIGHLY PURIFIED ALBUMINS ARE OBTAINED IN IMPROVED YIELDS FROM DIL BLOOD SERUM OR PLASMA BY NEARLY QUANTITATIVE ADSORPTION OF PROTEIN FRACTION BY A POLYELECTROLYTE POLYMER RESIN. THE RESIN IS PREPD BY COPOLYMERIZATION OF 1:1 ETHYLENE-MALEIC ANHYDRIDE & POST-TREATMENT WITH DIMETHYLAMINOPROPYLAMINE. PREPN ARE USEFUL IN SHOCK THERAPY & AS PLASMA EXPANDERS.

COLORIMETRIC METHOD DEVELOPED FOR DETECTING TRACE AMT IN AIR BASED ON REACTION WITH METHYL ORANGE. COLORED PRODUCT RECOVERED BY EXTRACTING WITH BUTANOL OR CHLOROFORM & DETECTED IN RANGE OF 0.8 TO 25 MG/CU M. METHOD IS RECOMMENDED FOR DETECTING CONCN IN AIR DURING TOXICOLOGICAL STUDIES AS WELL AS IN ENVIRONMENT OF WORKING AREA IN MFR & USE.

Fire Hazards -> Flammable - 3rd degree