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Home > Encyclopedia > 2-(Aminoiminomethyl)benzo[b]thiophen-6-ylester-2-Thiophenecarboxylicacid

2-(Aminoiminomethyl)benzo[b]thiophen-6-ylester-2-Thiophenecarboxylicacid

2-(Aminoiminomethyl)benzo[b]thiophen-6-ylester-2-Thiophenecarboxylicacid structure
  • CAS No:

    217099-43-9

  • Formula:

    C14H10N2O2S2

  • Synonyms:

    2-amidino-6-(2-thiophene carboxy)benzothiophene methanesulfonate;BCX 1470;BCX-1470;CHEMBL2220483;(2-carbamimidoyl-1-benzothiophen-6-yl) thiophene-2-carboxylate;2-(Aminoiminomethyl)benzo[b]thiophen-6-yl ester-2-Thiophenecarboxylic acid;cc-543;SCHEMBL7614663;DTXSID30431348

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Description

BCX 1470 inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.IC50 Value: 96 nM (Factor D); 1.6 nM (C1s); 326 nM (Trypsin) [1]Target: Factor D; C1sBCX 1470(Thrombin inhibitor) is serine protease inhibitor.BCX 1470(Thrombin inhibitor) blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro, also blocked development of RPA-induced edema in the rat.

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Basic Attributes

  • 217099-43-9

  • C14H10N2O2S2

  • 302.377

  • 302.018372

  • 132.65000

  • 3.71

  • OTGQTQBPQCRNRG-UHFFFAOYSA-N

  • 5

  • 2

  • 4

Characteristics

  • 1.5±0.1 g/cm3

  • 509.9±58.0 °C at 760 mmHg

  • 262.2±32.3 °C

  • 1.751

Safety Information

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