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Tirapazamine

Tirapazamine structure

CAS No:
27314-97-2
Formula:
C7H6N4O2
Chemical Name:
Tirapazamine
Synonyms:
1,2,4-Benzotriazin-3-amine,1,4-dioxide;1,2,4-Benzotriazine,3-amino-,1,4-dioxide;3-Amino-1,2,4-benzotriazine 1,4-dioxide;SR 4233;Tirapazamine;Win 59075;Tirazone;SR 259075;SML 0552;SR259075
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Tirapazamine is an anticancer agent that shows selective cytotoxicity for hypoxic cells in solid tumors, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death.

Tirapazamine Basic Attributes

Molecular Weight：

178.15

Exact Mass：

178.15

EC Number：

1533716-785-6

Characteristics

PSA：

88.4

XLogP3：

Appearance：

orange to dark orange-red

Density：

1.7±0.1 g/cm3

Melting Point：

222-224 °C

Boiling Point：

493.581°C at 760 mmHg

Flash Point：

252.3±24.0 °C

Refractive Index：

1.777

Water Solubility：

DMSO: soluble 10mg/mL, clear

Storage Conditions：

2-8°C

Vapor Pressure：

0mmHg at 25°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-36

RTECS Number：

DM0671500

Marks：

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

Tirapazamine Use and Manufacturing

A bioreductive anticancer agent.Selectively toxic to cells under hypoxic conditions.An antineoplastic

Recommended Suppliers of Tirapazamine

Anqing Rongchuang Biotechnology Co., Ltd Contact Supplier

CN
1 YR

Business licensed Certified factory

Manufactory Supplier of SR17018

Tirapazamine

CAS No.: 27314-97-2

Content: 98%

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