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apogossypol

apogossypol structure

CAS No:
66389-74-0
Formula:
C28H30O6
Chemical Name:
apogossypol
Synonyms:
apogossypol;(+)-Apogossypol;5,5"-Diisopropyl-3,3"-dimethyl-[2,2"-binaphthalene]-1,1",6,6",7,7"-hexaol;66389-74-0;Apogossypol;NSC736630;3-methyl-5-propan-2-yl-2-(1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)naphthalene-1,6,7-triol;NSC-736630;(2,2"-Binaphthalene)-1,1",6,6",7,7"-hexol, 5,5"-diisopropyl-3,3"-dimethyl-;Apogossypol; NSC736630

Description

(+)-Apogossypol is a pan-BCL-2 antagonist. (+)-Apogossypol binds to Mcl-1, Bcl-2 and Bcl-xL with EC50s of 2.6, 2.8 and 3.69 µM, respectively.

apogossypol Basic Attributes

Molecular Weight：

462.5 g/mol

Exact Mass：

462.204239 g/mol

Characteristics

PSA：

141.61000

XLogP3：

6.36570

Density：

1.335±0.06 g/cm3(Predicted)

Melting Point：

118-123 °C

Learn More Other Chemicals

APOGOSSYPOL HEXAACETATE

105201-55-6

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Guide of apogossypol

Description
Basic Attributes
Characteristics
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apogossypol

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