2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE
-
2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE
structure -
-
CAS No:
4943-85-5
-
Formula:
C14H14N2O
-
Chemical Name:
2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE
-
Synonyms:
2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE;BENZAMIDE, 2-AMINO-N-(2-METHYLPHENYL)-;OTAVA-BB 1133397;2-Amino-benzoesaeure-o-toluidid
- Categories:
-
CAS No:
2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE Use and Manufacturing
General procedure: Nitrobenzene (0.6mmol), 5wtpercent Pd/C (0.5mmol percent, 0.003mmol), H2O (10 equiv, 6.0mmol), B2(OH)4 (3.3 equiv, 2.0mmol), and CH3CN (1.0mL) were added in a 10mL tube. The reaction mixture was stirred at 50°C for 24h. When the reaction was complete monitored by TLC, the mixture was cooled to room temperature. Water (5mL) was added, and extracted with EtOAc (3×5mL). The combined organic phase was dried over anhydrous Na2SO4, filtered, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to give aniline 2a (55mg, 99percent).General procedure: Nitro aromatic (1.0 mmol), B2(OH)4 (5.0 equiv, 5.0 mmol), and H2O (3.0 mL) were added in a10 mL tube. The reaction mixture was stirred at 80 °C for 8 h. When the reaction was completemonitored by TLC, the mixture was cooled to room temperature, extracted with ethyl acetate (3 ×20 mL). The combined organic phase was dried over anhydrous Na2SO4, filtered, andconcentrated under reduced pressure. The residue was purified by silica gel columnchromatography.Example 69
Computed Properties
Molecular Weight:226.27
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:226.110613074
Monoisotopic Mass:226.110613074
Topological Polar Surface Area:55.1
Heavy Atom Count:17
Complexity:267
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE
-
![China]()
CN
6 YRS
Business licensed Certified factoryManufactory Supplier of chemicals -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate,Pigment & Dyestuff,Polymer,Flavour & Fragrance,Basic Organic Chemicals,PharmaceuticalInquiryCAS No.: 4943-85-5Grade: Pharmaceutical GradeContent: 96% -
![China]()
CN
5 YRS
Business licensedTrader Supplier of API OLED Organic intermediateInquiryCAS No.: 4943-85-5Grade: Industrial GradeContent: 98% -
![China]()
CN
3 YRS
Business licensedTrader Supplier of Fine chemicals and intermediatesInquiryCAS No.: 4943-85-5Grade: Good GradeContent: 99%
Learn More Other Chemicals
-
3-(3-CHLOROPROPYLCARBAMOYL)BENZENEBORONIC ACID
874288-10-5
-
3-Pyridinecarboxylic acid, 2,6-dichloro-, ethyl ester
58584-86-4
-
(+)-Mesembrenone
468-54-2
-
1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-, hydrochloride (1:1) Formula
230615-52-8
-
(4-acetyloxyphenyl)-(4-acetyloxyphenyl)imino-oxidoazanium Formula
79030-44-7
-
1-(4-Methoxy-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde Formula
347331-30-0
-
2,2'-DIAMINODIPHENYL SULFIDE Structure
5873-51-8
-
AC-ARG-PHE-MET-TRP-MET-ARG-NH2 Structure
152274-65-2
-
What is 1,1-Dimethylethyl 2-bromo-2-methylpropanoate
23877-12-5
-
What is 1,3-Dichloro-2,4-difluorobenzene
36556-37-3
2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE
SDSRequest for Quotation