 Home > Encyclopedia > 6-AMINOINDANONE

6-AMINOINDANONE

6-AMINOINDANONE structure

CAS No:
69975-65-1
Formula:
C9H9NO
Chemical Name:
6-AMINOINDANONE
Synonyms:
6-AMINO-1-INDANONE;6-AMINO-INDAN-1-ONE;6-AMINOINDANONE;6-Amino-2,3-dihydro-1H-inden-1-one;1H-Inden-1-one,6-amino-2,3-dihydro-;6-AMino-1-oxoindane;6-Amino-2,3-dihydro-1H-inden-1-one, 6-Amino-2,3-dihydro-1-oxo-1H-indene
Categories:
Chemical Reagents > Organic Reagents

Request for Quotation

6-AMINOINDANONE Basic Attributes

Molecular Weight：

147.17

Exact Mass：

147.068420

NSC Number：

225100

DSSTox ID：

DTXSID20310310

HScode：

2922399090

Characteristics

PSA：

43.1

XLogP3：

Appearance：

Light brown to black Solution

Density：

1.3±0.1 g/cm3

Melting Point：

167-171 °C(Solv: methanol (67-56-1))

Boiling Point：

330.3°C at 760 mmHg

Flash Point：

153.6±24.8 °C

Refractive Index：

1.650

Safety Information

Hazard category：

IRRITANT

Transport codes：

2811

hazard class code：

safety instructions：

Marks：

Precautionary statement(s)：

P264, P270, P280, P301+P312, P302+P352, P312, P322, P330, P363, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

6-AMINOINDANONE Use and Manufacturing

A mixture of the 6-nitroindan-1-one (10 g, 56 mmol) and 10percent Pd/C (2.Og) in MeOH (200 mL) was stirred under 30 psi of H6-Nitro-l-indanone (10.0 g, 56.4 mmol) was dissolved in methanol (200 mL) , a 10percent palladium-carbon powder (500 mg) was added, and the mixture was stirred at room temperature for 14 hr under a hydrogen atmosphere. To the reaction solution were added dichloromethane and ethyl acetate to dissolve the precipitated crystals, and the catalyst was filtered off. The filtrate was concentrated under reduced pressure, and the residue was washed with methanol to give the title compound (6.71 g, yield 81percent) .EXAMPLE 129B 6-amino-1-indanone [0367] A solution of Example 129A (19.68 g, 111 mmol) in ethanol (111 mL) was treated sequentially with iron powder (43.0 g, 770 mmol) and solid ammonium chloride (3.70 g, 69.2 mmol). The resulting suspension was stirred at 90° C. for 1 hour, cooled to room temperature, diluted with brine, and extracted with diethyl ether (4.x.100 mL). The combined organic layers were dried (MgSO4), filtered, and concentrated to provide the desired product as a 6:1 mixture of 6-amino- and 4-amino-1-indanone (14.20 g, 87percent). 1H NMR (300 MHz, DMSO-d6, 6-amino-1-indanone) δ 7.21 (d, 1H), 6.92 (dd, 1H), 6.75 (d, 1H), 5.27 (br s, 2H), 2.90 (t, 2H), 2.54 (m, 2H); 1H NMR (300 MHz, DMSO-d6), 4-amino-1-indanone) δ 7.10 (t, 1H), 6.81 (m, 2H), 2.80 (m, 2H), 2.59 (m, 2H).EXAMPLE 129B 8g of Intermediate 3 and 11g of Intermediate 2 were dissolved in an ethanol solvent, 7g of triethylamine was added, and the mixture was reacted at reflux for 5 hours.Cool naturally to room temperature, suction filter, The obtained milky white solid is intermediate 4

Computed Properties

Molecular Weight:147.17
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:147.068413911
Monoisotopic Mass:147.068413911
Topological Polar Surface Area:43.1
Heavy Atom Count:11
Complexity:178
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 6-AMINOINDANONE

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

6-Aminoindan-1-one

CAS No.: 69975-65-1

Content: 99.00%

Inquiry
Compound Net Biotechnology Inc. Contact Supplier

CN
2 YRS

Business licensed Certified factory

Manufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acid

69975-65-1 6-amino-2,3-dihydroinden-1-one

CAS No.: 69975-65-1

Grade: Industrial Grade

Content: 95%

Inquiry