2-AMINOCAPRIC ACID
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2-AMINOCAPRIC ACID
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CAS No:
17702-88-4
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Formula:
C10H21NO2
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Chemical Name:
2-AMINOCAPRIC ACID
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Synonyms:
D,L 2-AMINODECANOIC ACID;2-AMINOCAPRIC ACID;2-AMINODECANOIC ACID;2-Aminodecanoicacidpurum;DL-decyline [;2-AMINODECANOIC ACID PURUM 97%;(-)-D-2-Aminocapric acid;(R)-2-Aminodecanoic acid
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CAS No:
Characteristics
63.3
0.6
0.973±0.06 g/cm3(Predicted)
~262 °C (dec.)
300.9±25.0 °C(Predicted)
135.8±23.2 °C
1.468
2-AMINOCAPRIC ACID Use and Manufacturing
General procedure: Following the typical procedure described above, Rh(acac)(CO)2 (2.6 mg, 0.01 mmol), xantphos (28.9 mg, 0.05 mmol) were placed in the autoclave. Then a solution of olefin (5 mmol) in DME (8 mL) was added via cannula, the autoclave was pressurized with 20 bar of CO/H2 equimolar mixture and the reaction was conducted for 18 h, upon stirring, at 80°C. After this period, the reactor was cooled to room temperature, an aqueous solution (2 mL) of NH4Cl (5.5 mmol) and NaCN (5.5 mmol) was added via inlet cannula and the reaction was kept at 50°C for 20 h. After work-up and purification, the resulting α-aminonitrile (4.1 mmol) was suspended in a concentrated HCl solution and stirred for 6 h at 40°C. The product was dissolved in methanol. After adjustment of the pH to the isoelectric point, using NH4OH (aq), the solvent was evaporated and the amino acid was obtained.
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