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Home > Encyclopedia > 4-Amino-α-methylbenzeneacetonitrile

4-Amino-α-methylbenzeneacetonitrile

4-Amino-α-methylbenzeneacetonitrile structure

4-Amino-α-methylbenzeneacetonitrile 

structure
  • CAS No:

    28694-90-8

  • Formula:

    C9H10N2

  • Chemical Name:

    4-Amino-α-methylbenzeneacetonitrile

  • Synonyms:

    Benzeneacetonitrile,4-amino-α-methyl-;Hydratroponitrile,p-amino-;4-Amino-α-methylbenzeneacetonitrile;2-(4-Aminophenyl)propionitrile;4-Aminophenyl-α-methylacetonitrile;2-(p-Aminophenyl)propionitrile;2-(4-Aminophenyl)propanenitrile

4-Amino-α-methylbenzeneacetonitrile Basic Attributes

146.1891

146.19

249-164-7

2926909090

Characteristics

49.8

2.47708

1.081g/cm3

55-57°C

130-131 °C @ Press: 0.9 Torr

138.9ºC

1.573

0.000788mmHg at 25°C

Safety Information

IRRITANT

Xi

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

4-Amino-α-methylbenzeneacetonitrile Use and Manufacturing

Methods of Manufacturing

Use benzyl acetonitrile to react with dimethyl sulfate under alkaline conditions to generate 2-phenylpropionitrile, then nitrate and reduce to obtain the product.

Uses

Intermediates of flurbiprofen and pirprofen.

Computed Properties

Molecular Weight:146.19
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:146.084398327
Monoisotopic Mass:146.084398327
Topological Polar Surface Area:49.8
Heavy Atom Count:11
Complexity:160
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

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