 Home > Encyclopedia > 1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (αS)-, (2E)-2-butenedioate (1:1)

1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (αS)-, (2E)-2-butenedioate (1:1)

1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (αS)-, (2E)-2-butenedioate (1:1) structure

CAS No:
169675-09-6
Formula:
C11H12ClFN2.C4H4O4
Chemical Name:
1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (αS)-, (2E)-2-butenedioate (1:1)
Synonyms:
1H-Indole-1-ethanamine,6-chloro-5-fluoro-α-methyl-,(αS)-,(2E)-2-butenedioate (1:1);1H-Indole-1-ethanamine,6-chloro-5-fluoro-α-methyl-,(S)-,(E)-2-butenedioate (1:1);Ro 60-0175
Categories:
Organic Chemistry > Amides

Description

(2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine is a 1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine that has S configuration. A selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumarate salt. It has a role as a 5-hydroxytryptamine 2B receptor agonist and a 5-hydroxytryptamine 2C receptor agonist.

1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (αS)-, (2E)-2-butenedioate (1:1) Basic Attributes

Molecular Weight：

342.75

Exact Mass：

342.07800

Characteristics

PSA：

105.55000

XLogP3：

3.19310

Boiling Point：

353.2ºC at 760mmHg

Flash Point：

167.4ºC

Storage Conditions：

Desiccate at RT

Vapor Pressure：

3.65E-05mmHg at 25°C

Safety Information

Precautionary statement(s)：

P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362

Hazard Statements：

H315

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine fumarate

1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (αS)-, (2E)-2-butenedioate (1:1) Use and Manufacturing

Potent, selective 5-HT 2 receptor agonist; shows selectivity for the 5-HT 2C subtype (pK i values are 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT 2C , 2A , 1A , 6 and 7 receptors respectively). Centrally active following oral or systemic administration in vivo .

Computed Properties

Molecular Weight:226.68
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:226.0673042
Monoisotopic Mass:226.0673042
Topological Polar Surface Area:31
Heavy Atom Count:15
Complexity:227
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Latest News on 1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (αS)-, (2E)-2-butenedioate (1:1)

Learn More Other Chemicals

4,4′-(1,2-Diazenediyl)bis[N,N,N-trimethylbenzenaminium]

21704-61-0
N-(4-Chloro-2-methylphenyl)formamide

21787-81-5
Basic Blue 8

2185-87-7
3-tert-butyl-5-chloro-2-hydroxy-N-(2-nitrosophenyl)benzamide Formula

21889-00-9
1-Phenylcyclohexylamine Formula

2201-24-3
6-Hydroxymelatonin Formula

2208-41-5
Pyrrocaine Structure

2210-77-7
2-amino-N-(4-ethoxyphenyl)ethanesulfonamide Structure

22103-30-6
What is Bufeniode

22103-14-6
What is 4-(2-Quinolinyl)benzenamine

22191-97-5

Hot Searches: dipotassium.phosphate; butane price; ammoniumsulfate; best research chemical websites; petrol coke price; buy ammonium nitrate fertilizer online

Guide of 1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (αS)-, (2E)-2-butenedioate (1:1)

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Latest News
Learn More Other Chemicals

1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (αS)-, (2E)-2-butenedioate (1:1)

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.