2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid
-
![2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220811/85f40fedfdce4eeaa4f05ac1f15561f6.png "2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid")
2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid
structure -
-
CAS No:
140158-50-5
-
Formula:
C10H16N2O4
-
Chemical Name:
2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid
-
Synonyms:
4-Isoxazolepropanoic acid,α-amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-;α-Amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-4-isoxazolepropanoic acid;ATPA;2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid;(Rs)-2-amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoic acid;2-Amino-3-(5-(tert-butyl)-3-hydroxyisoxazol-4-yl)propanoic acid;2-Amino-3-(5-tert-butyl-3-hydroxy-1,2-oxazol-4-yl)propanoic acid;83654-14-2
-
CAS No:
Characteristics
102
-1.9
white solid
1.263±0.06 g/cm3(Predicted)
406.8ºC at 760mmHg
199.9ºC
1.529
DMSO: 10 mg/mL
Desiccate at +4°C
2.38E-07mmHg at 25°C
2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid Use and Manufacturing
A selective and potent GluR5 kainate receptor agonist (K i = 4.3 nM), inactive at GluR6 (K i > 1 mM) and only weakly active at AMPA receptors (GluR1-4) and the kainate receptors KA-2 and GluR7 (K i values of 6 - 14 μ M). Also available as part of the Kainate Receptor Tocriset™ .
Computed Properties
Molecular Weight:228.24
XLogP3:-1.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:228.11100700
Monoisotopic Mass:228.11100700
Topological Polar Surface Area:102
Heavy Atom Count:16
Complexity:354
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Learn More Other Chemicals
-
3,5-DIBROMO-2-[[[(3,5-DINITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
535965-38-9
-
3,5-DIBROMO-2-[[[[(2-CHLOROPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532386-89-3
-
3,5-DIBROMO-2-[[[(4-METHYL-3-NITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532943-48-9
-
3,5-DIBROMO-2-[[[[3-(2-FURANYL)-1-OXO-2-PROPENYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
586392-09-8
-
3,5-DIBROMO-2-[[[[(2-METHYLPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
531548-30-8
-
2-(1,8-dibromo-16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid Formula
333340-54-8
-
3,5-DIBROMO-2-[[[[3-(PHENOXYMETHYL)BENZOYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
586393-79-5
-
3,5-DIBROMO-2-[[[(4-CHLOROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
531530-32-2
-
What is 2-Cyclopentyl-3-(2,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-oxo-4-isoquinolinecarboxylic acid
400073-92-9
-
What is 9-Octadecenoic acid (9Z)-, compd. with N,N-dimethylcyclohexanamine (1:1)
65122-23-8
2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid
SDSRequest for Quotation