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Home > Encyclopedia > (βS)-β-Amino-3-fluorobenzeneethanol

(βS)-β-Amino-3-fluorobenzeneethanol

(βS)-β-Amino-3-fluorobenzeneethanol structure

(βS)-β-Amino-3-fluorobenzeneethanol 

structure
  • CAS No:

    325152-98-5

  • Formula:

    C8H10FNO

  • Chemical Name:

    (βS)-β-Amino-3-fluorobenzeneethanol

  • Synonyms:

    Benzeneethanol,β-amino-3-fluoro-,(βS)-;(βS)-β-Amino-3-fluorobenzeneethanol;(2S)-2-Amino-2-(3-fluorophenyl)ethanol;(S)-2-Amino-2-(3-fluorophenyl)ethanol

(βS)-β-Amino-3-fluorobenzeneethanol Basic Attributes

155.1695032

155.17

Characteristics

46.2

0.2

1.2±0.1 g/cm3

96-98 °C

127.0±23.2 °C

1.549

(βS)-β-Amino-3-fluorobenzeneethanol Use and Manufacturing

General procedure: At first, (Rs, 2S)-N-((tert-butyldimethylsilyloxy)-1-(4-fluorophenyl)ethyl)-2-methylpropane-2-sulfinamide 8a (0.280 g, 0.749 mmol) was dissolved in MeOH (10 mL) and then HCl/MeOH (4 M, 2.0 mL) was added. The mixture was stirred at room temperature for 3 h. The solvent was removed under vacuum and the residue neutralized with saturated NaHCOGeneral procedure: At first, (Rs, 2S)-N-((tert-butyldimethylsilyloxy)-1-(4-fluorophenyl)ethyl)-2-methylpropane-2-sulfinamide 8a (0.280 g, 0.749 mmol) was dissolved in MeOH (10 mL) and then HCl/MeOH (4 M, 2.0 mL) was added. The mixture was stirred at room temperature for 3 h. The solvent was removed under vacuum and the residue neutralized with saturated NaHCO

Computed Properties

Molecular Weight:155.17
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:155.074642105
Monoisotopic Mass:155.074642105
Topological Polar Surface Area:46.2
Heavy Atom Count:11
Complexity:121
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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