BIBP 3226
-
BIBP 3226
structure -
-
CAS No:
159013-54-4
-
Formula:
C27H31N5O3
-
Chemical Name:
BIBP 3226
-
Synonyms:
Benzeneacetamide,N-[(1R)-4-[(aminoiminomethyl)amino]-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl]-α-phenyl-;Benzeneacetamide,N-[4-[(aminoiminomethyl)amino]-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl]-α-phenyl-,(R)-;N-[(1R)-4-[(Aminoiminomethyl)amino]-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl]-α-phenylbenzeneacetamide;BIBP 3226;(2R)-5-(Diaminomethylideneamino)-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide
-
CAS No:
Drug Information
Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)
BIBP 3226
BIBP 3226 Use and Manufacturing
Mixed non-peptide neuropeptide Y Y 1 (NPY Y 1 ) and neuropeptide FF (NPFF) receptor antagonist (K i values are 1.1, 79, 108, > 1000, > 1000 and >1000 for rNPY Y 1 , hNPFF 2 , rNPFF, rNPY Y 2 , rNPY Y 4 and rNPY Y 5 respectively). Produces an anxiogenic-like effect in rats following i.c.v. administration.
Computed Properties
Molecular Weight:473.6
XLogP3:2.5
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:11
Exact Mass:473.24268987
Monoisotopic Mass:473.24268987
Topological Polar Surface Area:143
Heavy Atom Count:35
Complexity:658
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
