5-Bromo-1H-indole-3-ethanol

2-(5-Bromo-lflGeneral procedure: Other bromoethylarenes were prepared according to literature procedures as shown in the schemes below. Additional bromoethylindoles were prepared by Fischer-type indole synthesis followed by bromination (Campos, K.R. et al . 2004; Mewshaw, R.R. et al . 2004) (Scheme 16), acylation of substituted indoles with oxalyl chloride (Woodward, R.B. et al . 1958) followed by reduction (Feldman, et al . 1986) and bromination (Scheme 17) . 3- (2-bromoethyl) benzofuran (Kozikowski, A. P. et al . 2007; Tomaszewski, Z. et al . 1992) and 3- (2-bromoethyl ) benzothiophene were prepared according to the protocols in Scheme 18. 3-indolylacetaldehyde was prepared by Parikh-Doering oxidation of tryptophol (Sugawara, S. et al . 2009), 3- ( 2-oxoethyl ) -lH-indole-2-carboxylate was prepared from 2- (carboethoxy) indole via literature procedures (Buechi, G. et al . 1977; Vega, A.M. et al . 1981) , and 2- (2-chloroethyl ) benzimidazole was prepared by condensation of o-phenylenediamine and 3- chloropropionic acid (Cowart, M. et al . 2004) (Scheme 19) .

Molecular Weight:240.10
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:238.99458
Monoisotopic Mass:238.99458
Topological Polar Surface Area:36
Heavy Atom Count:13
Complexity:176
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes