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Calcium valproate

Calcium valproate structure

Calcium valproate 

structure
  • CAS No:

    33433-82-8

  • Formula:

    C8H16O2.1/2Ca

  • Chemical Name:

    Calcium valproate

  • Synonyms:

    Pentanoic acid,2-propyl-,calcium salt (2:1);Valeric acid,2-propyl-,calcium salt;Pentanoic acid,2-propyl-,calcium salt;Calcium α,α-dipropylacetate;Calcium dipropylacetate;Calcium valproate;Valproic acid calcium salt

Description

A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.

Calcium valproate Basic Attributes

326.49

326.17700

251-521-7

56CCK4F86G

DTXSID5020237

Characteristics

52.60000

4.42060

220ºC at 760 mmHg

116.6ºC

Safety Information

|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P264, P270, P280, P281, P301+P312, P302+P352, P305+P351+P338, P308+P313, P321, P330, P332+P313, P337+P313, P362, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)|Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)|Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function. (See all compounds classified as GABA Agents.)|Agents that are used to treat bipolar disorders or mania associated with other affective disorders. (See all compounds classified as Antimanic Agents.)

2 Propylpentanoic Acid

Computed Properties

Molecular Weight:326.48
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:326.1770003
Monoisotopic Mass:326.1770003
Topological Polar Surface Area:80.3
Heavy Atom Count:21
Complexity:87.9
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

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